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      community 21 months on topical minoxidil and full HRT

      in Transgender  214 upvotes 6 months ago
      The conversation is about a transgender individual's experience with hair regrowth using topical minoxidil and hormone replacement therapy (HRT), expressing concern about the slow growth and thin appearance of their hair. Some responses encourage patience and highlight the variability of results, while others discuss the role of HRT and its effects.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  136 upvotes 7 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Thin spots over time even with Finasteride

      in Progress Pictures  132 upvotes 7 months ago
      A user shared their experience with Finasteride for hair loss, noting improvement but still some thinning. They plan to get a hair transplant to address remaining thin spots and strengthen their hairline.

      community 9 months on fin and oral minoxidil (26M)

      in Progress Pictures  2324 upvotes 7 months ago
      A user shared their positive experience with hair regrowth after 9 months of using 1mg finasteride daily and 2.5mg oral minoxidil every other day, with no side effects. Other users expressed various reactions, from skepticism to hope, and discussed their own experiences with similar treatments.

      community Topical is superior to oral in terms of results (my theory)

      in Finasteride/Dutasteride  61 upvotes 7 months ago
      The conversation discusses the use of topical minoxidil and finasteride for hair loss, with some users combining them with oral treatments. Users share their experiences and opinions on effectiveness, cost, and convenience, with mixed views on whether topical or oral applications are superior.

      community bye fellas, it’s time to quit this sub

      in Progress Pictures  810 upvotes 7 months ago
      A user successfully improved their hairline after 15 months using topical minoxidil and dutasteride. Some commenters question the necessity of treatment given the user's original hair condition, while others support early intervention.

      community TRT. Pyrilutamide. Ru58841. Help

      in Treatment  3 upvotes 8 months ago
      A 30-year-old man experienced significant hair loss after starting testosterone replacement therapy (TRT), which did not improve with daily finasteride and minoxidil. He is considering restarting TRT and is seeking advice on using pyrilutamide or RU58841 to prevent further hair loss.

      community 1 year and half of just finasteride

      in Finasteride/Dutasteride  88 upvotes 8 months ago
      A user has been using finasteride for 1.5 years and reports significant improvement in hair quality and thickness, but not much change in hairline. They started with a big shed and take 0.5 mg daily.

      community I’m Feeling so discouraged and depressed - No one wants to prescribe finasteride to me.

      in Finasteride/Dutasteride  68 upvotes 8 months ago
      A user in France is frustrated because three dermatologists refused to prescribe finasteride for their hair loss, suggesting it's not androgenetic alopecia (AGA) and offering expensive vitamin treatments instead. Other users suggest buying hair loss treatments like minoxidil and finasteride from various online pharmacies and considering a gender-affirming care physician for more understanding treatment options.

      community Increasing Oral Minoxidil Dose Over Time

      in Research/Science  94 upvotes 8 months ago
      A user reports hair loss despite using minoxidil and plans to increase their oral minoxidil dose gradually while also taking finasteride, dermarolling weekly, and applying topical stemoxydine nightly. They shared a link suggesting that increasing minoxidil dosage can improve hair growth and thickness.

      community Which Minoxidil solution should i use?

      in Minoxidil  7 upvotes 8 months ago
      The user is using Minoxidil 5% with procapil spray and oral Minoxidil 2.5mg daily, and plans to add finasteride 1mg. They accidentally ordered a Minoxidil solution with finasteride 0.1% and are seeking advice on which to use.

      community Minox experimentation on pubic hair

      in Minoxidil  278 upvotes 8 months ago
      A user applied minoxidil to their pubic hair for 3 months, resulting in hair growth over 4 inches, and is considering using it for a scalp hair transplant. They plan to continue the treatment despite their wife's disapproval.

      community Finasteride suddenly stopped working for me after almost 2 years of using it (M19)

      in Finasteride/Dutasteride  10 upvotes 8 months ago
      A user reported that after nearly 2 years of using finasteride with initial hair regrowth, their hairline worsened around day 570 and has not improved significantly since. They are considering switching to dutasteride or changing finasteride brands, while responders suggest the user may not actually be experiencing hair loss and might benefit from professional help.

      community Creatine's effect on Hair Loss and DHT

      in Research/Science  103 upvotes 8 months ago
      A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

      community Theory And Observation: Why Being Bald Can Really Work

      in Shaved/buzzed  88 upvotes 9 months ago
      The original poster believes shaving his head made him more attractive to a specific group of women, despite being less attractive overall. The conversation includes various opinions on attractiveness, with some agreeing that being bald can work for certain men, while others suggest maintaining hair is generally more appealing.

      community Finasteride increase in Estradiol?

      in Update  17 upvotes 9 months ago
      A user experienced increased estradiol, nipple tenderness, and ED after taking finasteride. They are considering dose reduction to mitigate these effects.

      community Well here I am 3-4 years later.

      in Update  56 upvotes 9 months ago
      The conversation is about someone who has been taking finasteride for hair loss without success, considering switching to dutasteride or giving up treatment. Suggestions include trying dutasteride, microneedling, infrared therapy, multivitamins, and high-concentration topical solutions combining finasteride and dutasteride.

      community Any New Findings or Interesting Research?

      in Research/Science  25 upvotes 9 months ago
      The conversation is about seeking new research on hair loss treatments beyond the commonly known ones like Minoxidil and Finasteride. Additions to the list of treatments include topical caffeine, alfatradiol, fluridil, stemoxydine, and upcoming treatments like TDM-105795 and verteporfin.

      community Fin raised my estrogen but also testosterone?

      in Finasteride/Dutasteride  17 upvotes 9 months ago
      A user experienced initial side effects from finasteride, including erectile dysfunction and emotional changes, but later noticed increased muscle mass and assertiveness. Hormonal tests showed elevated estrogen and prolactin levels, which slightly decreased over time; the user plans lifestyle changes to see if they help.

      community Topical Finasteride strength discussion

      in Research/Science  66 upvotes 9 months ago
      The conversation discusses the effectiveness of different concentrations and dosages of topical finasteride on scalp and serum DHT levels, comparing it to oral finasteride and noting the side effects seem to be fewer at lower dosages. Participants shared experiences and referenced a chart indicating similar scalp DHT reduction with 0.025% topical finasteride as with 1mg oral finasteride, but with fewer side effects.

      community Found the solution tressbros - 1.5 years 2.5mg oral minox, 5mg finasteride, 8mg estradiol valerate (weekly)

      in Transgender  591 upvotes 10 months ago
      The conversation discusses a transgender individual's successful hair loss treatment over 1.5 years using 2.5mg oral minoxidil, 5mg finasteride, and 8mg weekly injectable estradiol valerate. Some users debate the appropriateness of this approach within the group's goals, while others support the individualized treatment and its additional benefits for transgender individuals.

      community Posted this years ago but still getting questions!

      in Progress Pictures  325 upvotes 10 months ago
      The user successfully treated their hair loss using 1ml of minoxidil twice daily and dermarolling with a 1.5mm dermaroller once a week. They experienced noticeable results only after combining minoxidil with dermarolling, and they have not used finasteride.

      community Exploring Bryan Johnson's Hair Routine In Detail

      in Research/Science  65 upvotes 10 months ago
      Bryan Johnson uses a custom hair loss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.