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      community Hair Loss Drugs Ranked in Order of Efficacy

      in Research/Science  67 upvotes 1 year ago
      Dutasteride is likely the most effective treatment for male pattern baldness, followed by finasteride and minoxidil in various forms and dosages. Users discuss personal experiences, dosages, and potential side effects, with some considering combining treatments for better results.
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      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  127 upvotes 1 year ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community How You Can Help Speed Up the Verteporfin Trials

      in Research/Science  185 upvotes 1 year ago
      The post discusses speeding up verteporfin trials for hair loss treatment. The original poster, involved in the trials, requests help in crowdsourcing doctor emails to spread awareness and gather more support for the trials.

      community Clascoterone (Winlevi) now approved in Canada

      in Product  13 upvotes 1 year ago
      The conversation is about the approval of Clascoterone (Winlevi) in Canada for hair loss treatment. One user expressed skepticism about its effectiveness due to low concentration.

      community Is Pyri worth it at the moment?

      in Chat  26 upvotes 1 year ago
      The conversation is about the effectiveness and safety of a hair loss treatment called Pyri, with users discussing its availability and comparing it to other treatments like RU58841, fluridil, and alfatradiol. Some users are waiting for FDA approval before using Pyri, while others share their positive experiences with RU58841 and suggest additional treatments with minimal side effects.

      community 7-month (fin/min/keto/micro) Progress [34M]

      in Progress Pictures  538 upvotes 1 year ago
      User shared 7-month progress of hair loss treatment, using daily 1mg Fin, 2x Min, monthly micro-needling, and ketocoz shampoo. They advise focusing on haircare, diet, and mental health after establishing a routine.

      community AnagenInc says GT20029 is possible now

      in Research/Science  117 upvotes 1 year ago
      AnagenInc is ready to produce a hair loss treatment called GT20029 if there is enough demand. People are discussing combining it with other treatments like finasteride and minoxidil, and some are concerned about the legitimacy and safety of gray market products.

      community Does melatonin dissolve in isopropyl alcohol

      in Technology  7 upvotes 1 year ago
      The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  40 upvotes 2 years ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community Are there alternatives to finasteride?

      in Research/Science  12 upvotes 2 years ago
      The conversation is about seeking alternatives to finasteride for hair loss treatment due to concerns about sexual side effects, with pyrilutamide mentioned as a potential alternative.

      community Action plan without finasteride

      in Product  7 upvotes 2 years ago
      A user shared their hair loss treatment plan using Revita tablets, Sulforaphane, Minoxidil, and microneedling, avoiding finasteride due to side effects. Replies suggest that without finasteride, the plan is unlikely to be effective, and recommend either using finasteride or shaving their head.

      community Pyrilutamide at 16 years old- update 2

      in Research/Science  21 upvotes 2 years ago
      A 16-year-old researching and trying Pyrilutamide for hair loss treatment, reporting back on side effects experienced after one week of use; the reported side effects included testicle pain, headache, and increased shedding. Libido and sexual performance seemed unaffected.

      community Is Pyrilutamide the real deal and if so when will it actually be available?

      in Chat  21 upvotes 2 years ago
      Pyrilutamide, a potential hair loss treatment that is currently in development and may be available soon; an androgen receptor degrader which is also being developed as a potential treatment for hair loss; and the comparison between Pyrilutamide, finasteride, minoxidil, and RU58841.

      community 2.5 months of oral minoxidil 5mg

      in Progress Pictures 2 years ago
      This conversation is about a user's progress with using oral minoxidil 5mg to treat their hair loss, in combination with finasteride. The replies discuss the effectiveness of this treatment and provide additional information on potential methods for obtaining it.

      community PYRILUTAMIDE KX-826 experience

      in Research/Science  97 upvotes 2 years ago
      A user's experience with the hair loss treatment Pyrilutamide KX-826, which has resulted in some side effects and shedding. The conversation also includes advice for baseline pictures and trying treatments for at least 6 months.
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      community 1 years update [Finasteride, 5 mg oral minoxidil and recently topical minoxidil with 1.5 mm dermarolling]

      in Progress Pictures  107 upvotes 2 years ago
      Making a 1 year update on hair loss treatment of Finasteride, 5 mg oral minoxidil and topical minoxidil with 1.5 mm dermarolling; the user experienced some face pimples, baggy eyes, and had tried skin care. They also used fiber with their hair product and left it for a few days to make it look visually better. Replies were positive and one asked if using both oral and topical minoxidil was overkill.

      community Starting Fluridil (Eucapil) Topical

      in Update  13 upvotes 2 years ago
      AltruisticBro's experience with Fluridil (Eucapil) as a hair loss treatment, and the current blood work results associated with it. They are not willing to take finasteride due to potential permanent side effects.

      community What’s the deal with pyrilutamide?

      in Research/Science  56 upvotes 2 years ago
      The effectiveness of pyrilutamide, a hair loss treatment, with research results being postponed until September. Various people shared their experiences with topical finasteride, minoxidil and RU58841, as well as other treatments such as dandruff shampoo, group buys and grey markets.

      community 26M Baseline blood work done before Finasteride

      in Finasteride/Dutasteride  8 upvotes 3 years ago
      A person considering finasteride for hair loss checked their hormone levels before starting treatment. They are concerned about the potential increase in estradiol and its effects, as well as the impact on their sex hormone-binding globulin (SHBG) and free testosterone levels.

      community Dutasteride questions

      in Finasteride/Dutasteride  6 upvotes 4 years ago
      Switching to dutasteride as a hair loss prevention treatment, along with minoxidil, dermarolling and nizoral shampoo, and the potential benefits and side effects of using finasteride and/or dutasteride in combination with topical anti-androgens like RU58841.