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GlossaryDopamine Agonists

medications that mimic dopamine by stimulating its brain receptors

Dopamine agonists, also known as dopamine receptor agonists or DA agonists, are medications that mimic the action of dopamine by stimulating dopamine receptors in the brain. They are commonly used to treat conditions like Parkinson's disease and restless legs syndrome by compensating for low dopamine levels, thereby improving symptoms such as motor control and mood.

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community What would hair loss treatment be like in the 2030s?

in Treatment 5 upvotes 5 months ago

The conversation discusses future hair loss treatments, with mentions of dutasteride potentially gaining FDA approval and increased popularity. Skepticism remains about significant advancements due to limited funding and reliance on cosmetic companies.

community Kintor’s KX-826 Pyrilutamide!!

in Research/Science 151 upvotes 3 years ago

KX-826 hair loss treatment completed trials with mild side effects. GT20029 may be ultimate cure, destroying androgen receptors causing baldness.

community Nandrolone Replacement Therapy

in Treatment 41 upvotes 1 year ago

A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.

community HMI 115 Phase 2 - Leaked pics from Discord

in Research/Science 366 upvotes 7 months ago

The conversation discusses HMI 115, a new hair loss treatment with promising results, showing a significant increase in hair density after two months. Some users are skeptical, while others are hopeful for its release and potential affordability.

community hmi115 is coming. Prepare yourselves for what's coming

in Technology 104 upvotes 1 year ago

The conversation discusses HMI-115, a potential cure for hair loss. Users share mixed opinions, with some expressing skepticism and others sharing anecdotal evidence of its effectiveness, including photos of significant hair regrowth from a trial participant.

community Do hair follicles dies or are dormant ?

in Finasteride/Dutasteride 92 upvotes 4 weeks ago

Hair follicles can be dormant and potentially revived with treatments like finasteride and minoxidil, but irreversible loss occurs if certain structures are destroyed. Early intervention is more effective, and additional methods like microneedling may help.

community Mucuna pruriens, dopamine and prolactin. Natural route with oils.

in Treatment 2 upvotes 1 year ago

The post discusses using Mucuna pruriens, essential oils, and dermarolling for hair loss treatment. The user also mentions pausing testosterone-boosting herbs due to side effects like acne and hair loss.

community Trestolone (MENT) as a nuclear treatment

in Treatment 99 upvotes 2 years ago

Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

community does lowering your prolactin levels regrow hair?

in Research/Science 10 upvotes 1 year ago

The potential of lowering prolactin levels to regrow hair, with a reference to Bayer's drug HMI 115 which has been indicated as having this effect. Treatments mentioned include Minoxidil and Finasteride, as well as RU58841.

community Diagnosed with female pattern hair loss as a male with recent aggressive loss. Preemptively mourning the only part of myself I’ve ever come close to loving. Lost all motivation to do anything with my life.

in Progress Pictures 271 upvotes 1 year ago

The conclusion of the conversation is that the user should consider using treatments such as finasteride, minoxidil, and RU58841 to potentially reverse their hair loss. Other suggestions include using hair loss concealers and maintaining a healthy diet.

community People who tolerate dut better than fin?

in Finasteride/Dutasteride 32 upvotes 2 months ago

Dutasteride may have fewer side effects than finasteride, with some users experiencing better hair maintenance. Experiences vary, with some preferring dutasteride for fewer side effects, while others see no significant hair improvement.

community Female, 27 years old, shedding/ balding despite being on what is considered to be a effective treatment plan for AGA. Considering Dut (oral) . Please help.

in Finasteride/Dutasteride 27 upvotes 2 months ago

A 27-year-old woman with androgenic alopecia is losing hair despite using oral minoxidil and spironolactone, and is considering dutasteride. She is exploring causes like stress and medication side effects, planning tests, and considering treatment changes.

community Finasteride and Its Effects on Cognition: Where's the Science?

in Research/Science 26 upvotes 4 years ago

The user shared their experience with hair loss treatments, including low-dose minoxidil, finasteride, and essential oils, and expressed concerns about the cognitive side effects of finasteride. They are seeking more information on how finasteride may affect cognition and are considering whether to continue or stop the treatment.

community Why does finasteride stop working?

in Finasteride/Dutasteride 26 upvotes 2 months ago

Finasteride may seem less effective over time due to increased DHT sensitivity or aging, but it still suppresses DHT. Switching to dutasteride offers stronger DHT suppression but may increase estrogen levels.

community Almost 3 months | Topical Min (5%), 1 mg Fin, Microneedling, Biotin + Vitamin D Supplement

in Progress Pictures 601 upvotes 1 year ago

The conversation discusses a successful hair regrowth treatment involving topical Minoxidil (5%), 1 mg Finasteride, Microneedling, and Biotin + Vitamin D supplements. The user shares their routine and receives positive feedback on the significant progress made in just three months.

community Horrible news, Stemson Therapeutics has shut down

in Technology 193 upvotes 1 week ago

Stemson Therapeutics has shut down, disappointing those seeking a hair loss cure. Current treatments like minoxidil, finasteride, and dutasteride are discussed, with some users experiencing side effects and exploring alternatives like PP405.

community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 8 months ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

community 35 MtF | 16 Months | Minoxidil + Dutasteride + Microneedling + Exosomes. Note that since I'm early in my transition (and I was coming from a bald state), I still have short hair. Very few MtF progress pictures here, I figure this might help some of you.

in Transgender 128 upvotes 1 year ago

A 35-year-old transitioning female (MtF) shared her hair regrowth journey using Minoxidil, Dutasteride, Microneedling, and Exosomes, starting from a bald state. Commenters discussed the impressive results, skin care routine, and the effects of estrogen on hair and skin.

community Hope Medicine announces HMI-115 phase II clinical trial for androgenetic alopecia in China

in Research/Science 55 upvotes 1 year ago

Hope Medicine's announcement of the HMI-115 Phase II clinical trial for androgenetic alopecia in China; other related trials have been conducted or are ongoing in different countries, including Australia, US, and Europe. There is speculation that the product may be accepted across borders without additional testing.

community Topical Finasteride reduced my DHT more than Oral Dutasteride

in Finasteride/Dutasteride 42 upvotes 2 years ago

Treatments for hair loss, including the experiences of topical finasteride and oral dutasteride. It also discusses Pyrilutamide, 0.025% topical concentration, Minoxidil, RU58841, and 1% finasteride gel dosage.

community Dutasteride is possibly BETTER for the brain than Finasteride

in Finasteride/Dutasteride 23 upvotes 8 months ago

Dutasteride may be better for the brain than Finasteride, potentially increasing dopamine levels and causing fewer side effects. For those switching from Finasteride to Dutasteride to prevent hair loss, it's recommended to continue Finasteride for 3-4 months while starting Dutasteride to avoid shedding due to Dutasteride's long half-life.

community I've been afflicted by post finasteride syndrome, what now?

in Finasteride 42 upvotes 5 years ago

A user experienced severe side effects from finasteride, including mental health issues and physical symptoms, and sought advice on managing post-finasteride syndrome. Suggestions included checking vitamin levels, considering dopamine agonists, and avoiding further psychiatric medications.

community Debunking the "Adverse metabolic consequences of dutasteride"

in Research/Science 40 upvotes 3 years ago

Dutasteride is more effective than finasteride, has neuroprotective benefits, and may prevent acne. Despite initial concerns about metabolic effects, further research suggests it is safe for most users, especially if not hypogonadal.

community 4months fin and dermarolling prog

in Progress Pictures 7 upvotes 6 months ago

User shares progress after 4 months of using finasteride and dermarolling, with occasional use of coconut and rosemary oil. They aim to stop hair loss and hope for increased top density.

community Do any of you guys feel like your 20s have been wasted?

in Chat 184 upvotes 7 months ago

A user expressed frustration about hair loss and its impact on their 20s, mentioning financial struggles and mental health concerns. Responses included advice on positive thinking, self-improvement, and seeking treatment options like Minoxidil and finasteride.

community Taking finasteride turned me bicurious - a cautionary tale.

in Satire 623 upvotes 1 year ago

A user's experience taking finasteride, which resulted in them having an unexpected emotional reaction, and the replies to this post focus on the humorous aspects of cautionary tales about hair loss treatments.

community Reminder how little the average person knows about hair loss

in Satire 642 upvotes 2 years ago

How little the average person knows about hair loss and how it can be an unfairly stigmatized issue, even by people with little knowledge of it themselves. Some specific treatments that were discussed include finasteride, RU58841, dutasteride, minoxidil, pyritinol, dermarolling, and diet/lifestyle changes.

community Guys. Your hairloss and your mental health issues connected to your hairloss are two separate issues that require two separate treatments

in Chat 356 upvotes 2 years ago

Hair loss and the importance of not letting it affect one's self-worth. The conversation includes advice on treatments such as taking medication, like Minoxidil and Finasteride, and other methods to manage hairloss, such as buzzing your head or seeking professional help.

community Why do people who do hard drugs have great hair?

in Chat 10 upvotes 3 years ago

The conversation discusses why some people who use hard drugs have great hair, with various opinions suggesting genetics and higher estrogen levels as possible reasons. Specific treatments like Minoxidil, finasteride, and RU58841 are not mentioned.

community How I started reversing Male Pattern Baldness naturally ?

in Question 6 upvotes 7 years ago

The user reversed male pattern baldness using a pro-thyroid diet, lifestyle changes, and scalp stimulation exercises, without Minoxidil or Finasteride. They reported reduced dandruff, itchiness, oiliness, and experienced hair regrowth and thickening over 15 months.