TWIST-1 gene's role in hairloss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.
Botox is found to be as effective as finasteride in treating hairloss. Users discuss combining treatments like botox, minoxidil, and massages for better results.
This user experienced severe hairloss, but was able to successfully treat it with finasteride over a two year period. Despite experiencing multiple shedding cycles while on the medication, Mission5896 reported that their hair continued to get thicker and stronger. Additionally, they tried both minoxidil orally and topically, but only found success with finasteride.
The conversation discusses whether sunlight exposure affects hair growth or loss, with mixed anecdotes and theories but no clear consensus. Some suggest moderate sunlight can benefit hair by providing vitamin D, while others doubt its effectiveness compared to treatments like Minoxidil or finasteride.
A potential treatment for hairloss that involves injecting fat into the scalp; the role of testosterone and estrogen in thinning fat tissue under the skin; research on using lard to treat androgenic alopecia, as well as PRP + ACELL/amniotic stem cell treatments; and ongoing clinical trials by doctors involved in the study.
The conversation is about hairloss and the conclusion is that genetics play a significant role in hairloss, and lifestyle choices or being a well-adjusted person do not prevent male pattern baldness.
The conversation is about someone who has been taking finasteride for hairloss without success, considering switching to dutasteride or giving up treatment. Suggestions include trying dutasteride, microneedling, infrared therapy, multivitamins, and high-concentration topical solutions combining finasteride and dutasteride.
A user is losing hope after 5 months on finasteride, seeing more hairloss and minimal positive changes. Another user advises that shedding is normal and benefits may take up to 2 years.
Users discuss their positive experiences with finasteride for hairloss, mentioning halted hairloss, hair regrowth, and improved self-esteem. Some express satisfaction in taking action against baldness, while others note increased libido and energy.
Hairloss treatments, including minoxidil, dermarolling, finasteride, dutasteride, hair transplants, hair systems, and shaving the head. The conversation covers various opinions on these treatments and mentions possible side effects as well as alternatives like wigs, vitamins, and lifestyle changes. The post expresses disappointment that there has been no major breakthrough in the field of hairloss treatments despite decades of research.
User has been on finasteride and switched to Dutasteride 6 months ago, using minoxidil, tretinoin, microneedling, and RU-58841, but still experiencing hairloss. Advice given includes waiting 6-18 months for Dutasteride results and checking if it's definitely MPB.
A user's decision to shave their head after experiencing hairloss since the age of 17, and discussion around the potential use of Fin for treating hairloss.
People discussing their experiences with natural treatments for hairloss, such as essential oils, deep scalp massages, anti-inflammatory measures, and supplements. Most of the replies suggest that these treatments are not effective and recommend medication such as minoxidil or finasteride instead.
User TopBack56 and friends tried pyrilutamide (KX-826) for hairloss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.
A 23-year-old male experiencing worsening hairloss has tried topical Minoxidil, Finasteride, Progesterone, Hydrocortisone butyrate, and Ketoconazole. He is considering switching to oral Finasteride due to concerns about side effects and lack of improvement.
Minoxidil can prevent hair follicle miniaturization, not just stimulate hair growth. Finasteride and dutasteride don't work for everyone, suggesting DHT may not be the sole cause of hairloss; hairloss could be due to multiple factors, including autoimmune conditions.
A user stopped finasteride due to side effects and rapid hairloss, considering a hair system. Others suggested alternatives like dutasteride, minoxidil, and topical finasteride.
TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.
The post discusses the experiences of individuals with diffuse hair thinning using finasteride, with many reporting no improvement or worsening conditions after 6 months. Various suggestions include persisting with the treatment, checking for underlying conditions, adding minoxidil for volume, adjusting dosage, and considering other potential causes like autoimmune responses and inflammation.
A 34-year-old man successfully regrew hair using a routine of Hims finasteride/minoxidil spray, biotin, multivitamins, Nizoral 1% keto shampoo, and derma rolling. He also mentioned lifestyle changes like quitting alcohol, stopping creatine, and regular exercise.
User had a hair transplant and used a finasteride and minoxidil spray for 6 months with no results. After adding finasteride tablets for 1 month, they saw significant hair growth improvement.
A user has been on dutasteride for nearly 2 years with no improvement in hairloss, expressing frustration. Other users suggest checking for other health conditions, getting bloodwork, and considering stopping TRT or trying finasteride.
A user experienced significant hair shedding and thinning 10 months post-hair transplant despite using minoxidil and topical finasteride. They are considering switching to oral finasteride or dutasteride and are also dealing with scalp conditions like seborrheic dermatitis.
The conversation discusses a new 0.3% tretinoin topical launched by MinoxidilMax for mixing with other solutions, with some users expressing concern about potential skin irritation compared to lower concentrations. MinoxidilMax has also released other products like topical Dutasteride and RU58841.
After 11 years on Finasteride, a user's hair is thinning again, suggesting hair may become more sensitive to DHT with age. They plan to introduce Dutasteride once a week, as they cannot tolerate Minoxidil.
The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.
The user started using finasteride, minoxidil, and biotin for male pattern baldness (MPB) and is experiencing rapid thinning. They are questioning if low blood flow to the head could be contributing to their hairloss.
The conclusion of the conversation is that the user has experienced significant hair regrowth using a combination of medications, including dutasteride, RU58841, and minoxidil. They have not experienced any noticeable side effects and are considering a hair transplant in the future.
The conversation discusses androgenic alopecia (AGA) and its treatments, focusing on finasteride, minoxidil, and ketoconazole shampoo. Finasteride is recommended as essential for preventing further hairloss.