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      community Chlorine dioxide: An effective product?

       5 upvotes 1 year ago
      Chlorine dioxide was discussed as a potential hair growth treatment, with a method involving spraying it on the scalp and covering it with a cap. Concerns were raised about its safety, comparing it to bleach.

      community Solvent for topical fin with low absorption

       2 upvotes 2 years ago
      The conversation is about using distilled water as a solvent for topical finasteride to reduce systemic absorption. The user is considering avoiding ethanol and propylene glycol to achieve this.

      community fluridil (topilutamide) vs. cb-03-01 (clascoterone)

       4 upvotes 2 years ago
      The conversation is about comparing the effectiveness of fluridil and clascoterone in preventing hair loss and inquiring about their use as standalone treatments. There is a question about the concentration of the fluridil brand for efficacy.

      community Duta solution with no oil or pg

       1 upvotes 1 year ago
      The conversation is about finding a Duta solution without PG, DMSO, glycerin, or oils, using only ethanol or alcohol. It suggests that such a solution may need to be made personally, as it is not readily available.

      community Clascoterone is the way to go if you cannot use DHT blockers

       11 upvotes 4 months ago
      Clascoterone is suggested as an alternative for those who experience side effects from finasteride and dutasteride. It is not widely available yet, but some users are obtaining it from compounding pharmacies or suppliers like Echemi.

      community clascoterone powder to topical diy

       4 upvotes 4 months ago
      The conversation is about making a topical solution from clascoterone powder, with references to using a RU58841 mixing guide for guidance. Concerns about product authenticity and bulk purchase requirements are also discussed.

      community Trial for TDM-105795 update from research office

       16 upvotes 2 years ago
      The trial for TDM-105795 has been completed, and it was in phase 2A. The discussion seeks input on the next phases, 2B or 3, based on safety and efficacy.

      community PP405 (Everychem 3HP) Users - Assemble and share your story!

      in Chat  19 upvotes 4 months ago
      Users discussed the effectiveness of Everychem's solution, similar to PP405, with some reporting improved hair thickness and new growth. Concerns were raised about safety and the legitimacy of the product, with some users advising against purchasing research chemicals.

      community Having Ru58841 mailed to my house

      in Research/Science  1 upvotes 7 months ago
      RU58841 can be ordered as a powder and compounded at home, but it should be stored at room temperature to avoid crystallization. Pyraulatmide may follow a similar principle.

      community Diy dutesteride please help MCT oil or PG?

       1 upvotes 9 months ago
      A user is making their own dutasteride solution using MCT oil but is concerned about its effectiveness and bioavailability. They are considering using propylene glycol or adding ethanol for better results, while others suggest the current dosage might be excessive.

      community Clascoterone - what we have right now

       24 upvotes 6 months ago
      Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

      community Whats the deal with TDM-105795?

      in Research/Science  4 upvotes 6 months ago
      TDM-105795 is a potential hair growth stimulant that works differently from minoxidil and could be used alongside it for enhanced growth. It completed phase 2 trials in 2024, with a medium to high chance of release in 2026, but lacks recent updates or phase 3 trial information.

      community Why is clascosterone (cb0301) so expensive ?

       3 upvotes 1 month ago
      Clascosterone (CB0301) is expensive due to concentrated form and lack of market competition. Users discuss sourcing from Indian and Chinese pharmacies for cheaper alternatives, but express concerns about product quality.

      community Why was fluridil abandoned and never made past phase 2?

       5 upvotes 4 years ago
      Fluridil was abandoned due to its weak effectiveness and low binding affinity to the androgen receptor, making it less competitive against DHT and testosterone. Users discuss its limited results compared to other treatments like pyrilutamide and RU58841.

      community How should i formulate my solvent for topical finasteride?

       1 upvotes 1 year ago
      The conversation is about formulating a solvent for topical finasteride without using propylene glycol. Suggestions include using ethanol, glycerin, and distilled water in various ratios, with some discussion on the use of emulsifiers.

      community Clascoterone powder already available?

       4 upvotes 5 months ago
      Clascoterone powder is now available, but it's expensive and not widely discussed due to past ineffective results at higher concentrations. Users are skeptical about its effectiveness and are seeking reliable sources.

      community 5 months MTF HRT no min/fin/dut

       35 upvotes 2 years ago
      A 22-year-old trans woman has been on 6mg estradiol enanthate for five months. She reports thicker and healthier hair but not much regrowth yet.

      community European release of clascoterone

       13 upvotes 4 months ago
      Clascoterone's European release is expected in Q4 2026, with FDA approval anticipated by mid-2027. The discussion includes questions about the approval timeline and potential acceleration due to unmet needs.

      community Ordering ethanol in the UK. Any tips?

      in Finasteride/Dutasteride  1 upvotes 5 months ago
      A user is seeking advice on ordering ethanol in the UK to use with topical finasteride, considering switching from isopropyl alcohol. They mention the possibility of purchasing 99.8% ethanol from eBay's 6 Science shop.

      community Clascoterone 5% solution infographic

       130 upvotes 9 months ago
      Clascoterone 5% solution is discussed as a potential new treatment for hair loss, offering an alternative for those who can't use finasteride or need additional options beyond minoxidil. Concerns about cost, effectiveness, and safety compared to existing treatments like RU58841 and finasteride are highlighted.

      community Topical fin solubility and stability in dilution

       3 upvotes 1 year ago
      The conversation discusses concerns about the solubility and stability of topical finasteride (Fynzur) when diluted with ethanol and distilled water, without propylene glycol. The user is worried about the even distribution of finasteride in the solution.

      community Making my own topical finasteride - ethanol question

       4 upvotes 3 years ago
      The conversation is about making topical finasteride using ethanol. The user is advised to use non-denatured or food-grade ethanol, as denatured ethanol may be harmful with prolonged skin exposure.

      community Where to find ethanol for RU powder

       5 upvotes 4 years ago
      The conversation is about finding ethanol in California for mixing with RU58841 for hair loss treatment. Users suggest alternatives like high-proof alcohol from liquor stores or purchasing lab-grade ethanol online.

      community My personal thoughts on DHT. belive it or not

      1 year ago
      The conversation discusses a personal theory on the role of DHT in stress and reproduction, suggesting it converts testosterone for reproductive traits. The discussion includes skepticism and mentions individual differences in physiology and neurochemistry.