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The conversation discusses the severe shedding caused by Minoxidil, with users sharing their experiences and outcomes. Some report eventual regrowth, while others see no improvement or worsening hair loss.

An 18-year-old using Minoxidil 2% for hair loss is considering adding dermarolling to their routine. Replies suggest adding finasteride, using a dermastamp, and microneedling, with positive experiences shared.

A user shared progress pictures after 8 months of using topical 5% minoxidil and 0.01% finasteride, showing significant hair regrowth. Replies suggest the user might not need a hair transplant and recommend considering oral finasteride.

A user reported that Procerin, containing Saw Palmetto and Pumpkin seed oil, provided similar hair thickening results as finasteride but with milder side effects. They experienced reduced libido and watery ejaculations but are adjusting the dose to minimize these effects.

User had a hair transplant and used a finasteride and minoxidil spray for 6 months with no results. After adding finasteride tablets for 1 month, they saw significant hair growth improvement.

RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

The conversation is about overcoming fear of finasteride/dutasteride for hair loss treatment. Users suggest starting with a small supply, noting side effects are rare and reversible, and emphasize personal comfort and confidence.

A user experienced no reduction in DHT levels after 8 months of finasteride, despite initial improvement in hair loss. They are considering switching to dutasteride but are concerned about potential side effects.

A user shared their experience with finasteride for hair loss, noting it slowed but didn't stop their hair loss, and they quit after 1.5 years. Suggestions included trying dutasteride, adding minoxidil, and maintaining a healthy lifestyle.

A 36-year-old considering a fourth hair transplant is advised to either shave his head or use a hair system due to poor results from previous transplants and late medication use. He plans to consult top surgeons and adjust his current treatments, including finasteride and minoxidil.

Dr. Oscar Muñoz's hair loss treatment tier list suggests oral minoxidil and finasteride are highly effective, while topical treatments like RU58841 and microneedling are less effective. Users discuss the effectiveness of various treatments, with some favoring oral options for their practicality and higher response rates.

A user reported a 50% increase in testosterone after 18 months of taking dutasteride for hair loss. The conversation includes skepticism about the reliability of single testosterone tests and questions about estrogen levels.

Users discuss using pyrilutamide for hair loss, seeking alternatives to 5AR inhibitors. They mention using minoxidil, ketoconazole shampoo, and RU58841.

Glycosaminoglycans are important for hair growth, and combining minoxidil with tretinoin and Biopeptide-CL may enhance hair growth by boosting glycosaminoglycan levels and improving the hair follicle environment. Users discussed the potential effectiveness and future of these treatments.

The conversation discusses using very low dose topical finasteride to achieve specific serum DHT reduction percentages. It concludes that finasteride dosage increases linearly between 5-30% DHT reduction but requires exponential increases for reductions up to 70%.

An 18-year-old is experiencing worsening hair loss, feeling isolated, and considering treatments like Minoxidil and finasteride. Others suggest seeing a dermatologist to determine the cause and potential treatments.

A user shared their 10.5-month progress using oral finasteride, topical minoxidil, a derma roller, biotin, and Omega 3, despite losing over 150 hairs daily. They also mentioned starting "bald showers" after leg workouts for the last two months.

Joe Biden aged significantly between ages 25 and 30, with noticeable changes in hair and facial features. He had a hair transplant, but it's unclear if he used Minoxidil or Finasteride.

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

A user experienced severe hair shedding and hairline recession after 10 months on finasteride. They are considering switching to dutasteride or adding minoxidil.

Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

A user convinced their 45-year-old dad to use minoxidil and finasteride, resulting in significant hair regrowth. The dad now uses 1mg of finasteride daily and topical minoxidil twice a day, and has also started using 1% ketoconazole shampoo.

A user experienced a hard lump under their nipple and increased hair loss after four months of finasteride. They are concerned about the lump and plan to stop the treatment.

David Barreto shared that a London-based research group is conducting a 12-month trial for a new nutraceutical treatment for pattern hair loss, designed with Dr. Carlos Puig. The trial aims to provide robust data, with results expected in 1-2 years, potentially representing a significant advancement since finasteride’s introduction in 1997.

Topical finasteride is considered a safer option for hair regrowth with fewer systemic side effects compared to oral finasteride. Some users report similar efficacy and side effects between topical and oral treatments, while others prefer topical due to reduced systemic exposure.

A 24-year-old shares a 1-month update on his hair regrowth journey using 1mg oral finasteride, 10mg oral minoxidil, dermarolling, and pyrilutamide. Replies suggest it may take a few hair cycles for vellus hairs to mature into normal hairs, with progress varying by individual.

A user shared their one-year results using finasteride and minoxidil for hair loss, showing noticeable improvement. They started seeing results at six months, using 1ml liquid twice a day and a pill once a day.

A user shared their 2+ years progress on Oral Dutasteride and Sublingual Minoxidil for hair loss. Another user asked about the form of Minoxidil used sublingually.

A 49-year-old user shared progress pictures after six months of using oral finasteride (1mg), oral minoxidil (2.5mg), and ketoconazole shampoo twice a week, reporting no side effects.