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      community Twist1 Group Buy: Yes it’s that easy

      in Research/Science  39 upvotes 2 years ago
      A group buy for testing a compound targeting Twist1 protein as a potential hair loss treatment. Inhibiting Twist1, which keeps hair follicles in growth phase, may prevent hair loss with minimal side effects.

      community The story of RU58841/PSK3841

      in Research/Science 5 months ago
      RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

      community Getting tretinoin in Spain 🇪🇸

      in Product  3 upvotes 5 months ago
      Tretinoin for hair loss in Spain may require a prescription and is often available compounded with minoxidil. Users are discussing how to obtain it.

      community GT20029. Kintor Pharma’s Product

      in Research/Science  12 upvotes 2 years ago
      The conversation discusses GT20029, a compound by Kintor Pharma that degrades androgen receptors and is in trials, with potential as a hair loss cure. Another promising treatment mentioned is an antibody that blocks prolactin and has shown positive results in macaques.

      community Does anyone have experience with topical dut?

      in Finasteride/Dutasteride  8 upvotes 2 years ago
      The user has been using minoxidil for hair loss and is considering trying a compounded topical treatment with 0.1% dutasteride, minoxidil, tretinoin, collagen, and silicon, as recommended by a trichologist. They learned that dutasteride might be more effective than finasteride and are seeking opinions on the use of topical dutasteride.

      community No-Finasteride Regime

      in Treatment  10 upvotes 3 years ago
      User explores no-finasteride hair loss treatments, considering compounds like Minoxidil, Eucapil, Alfatradiol, Stemoxydeine, Azelaic Acid, Retinol, and Ketoconazole Shampoo. They ask about mixing compounds, application schedules, and potential side effects.

      community Estimate of GT20029 on the grey market?

      in Technology  9 upvotes 1 year ago
      The conversation is about when GT20029, a hair loss treatment, might be available on the grey market, with users discussing the challenges of compounding it and speculating it might be available after phase 2 results, similar to pyri. Specific treatments mentioned are pyri, RU58841, and GT20029.

      community Updates about KX-826 & GT20029

      in Research/Science  16 upvotes 1 year ago
      The conversation discusses potential advancements in two hair loss drugs, KX-826 and GT20029, and the interest in whether transitioning from oral finasteride to these drugs would maintain hair growth. One reply expresses skepticism about the compounds' representation.

      community Using Topical Minoxidil And Pyrilutamide Together

      in Treatment  1 upvotes 5 months ago
      Mixing 1ml of topical Minoxidil and Pyrilutamide (2ml total) together in a container and applying immediately is being discussed. The concern is whether this method degrades or compromises the efficacy of either compound.

      community When will WINLEVI be available?

      in Finasteride/Dutasteride  7 upvotes 3 years ago
      The conversation is about the availability of WINLEVI, a hair loss treatment, and the possibility of getting it compounded. The user is seeking information on when they can obtain the treatment.

      community 1 year on fin and min results

      in Progress Pictures  47 upvotes 4 years ago
      The user has been using finasteride and minoxidil since September 2019 and has seen significant hair regrowth. Their routine includes a compounded topical with minoxidil, finasteride, dutasteride, and retinol at night, and 1mg finasteride in the morning.

      community Where can I buy dutasteride powder?

      in Finasteride/Dutasteride  13 upvotes 2 months ago
      The conversation is about sourcing dutasteride powder for hair loss treatment, with users suggesting websites like Alibaba and Made-in-China for purchasing. Users discuss the challenges of compounding pills and the legitimacy of online sources.

      community M29 Dut/Min/Microneedle/Tretinoin

      in Is this regrowth?  23 upvotes 6 months ago
      A user has been using finasteride since 2018, switched to dutasteride, and added minoxidil, microneedling, and a tretinoin/spiro compound. They are pleased with the results and hopeful for more improvement.

      community Anyone using Finastopic (no pg Isdin)?

      in Product  2 upvotes 8 months ago
      The conversation discusses the use of Finastopic, a carrier for finasteride solutions by Isdin, and compares it to a standard propylene glycol (PG) solution. The user was prescribed a 1% finasteride solution using Finastopic and has been using a self-compounded 0.025% topical finasteride with minoxidil.

      community 1.5 Year Hair Restoration Journey - Stem Cells, PRP, Minoxidil, Topical Finasteride

      in Progress Pictures  26 upvotes 10 months ago
      A user shared their 1.5-year hair restoration journey, successfully using mesenchymal stem cell therapy, Platelet Rich Plasma (PRP) injections, and a topical compound of finasteride and minoxidil, avoiding a hair transplant and oral finasteride. They experienced significant hair regrowth, particularly crediting the stem cell therapy for quick initial results.

      community Whats up with Prolactine these days?

      in Research/Science  20 upvotes 1 year ago
      The conversation discusses the potential role of prolactin in hair loss and mentions treatments like HMI115, mucuna pruriens, Zinc, and B6 P5P for lowering prolactin levels. It also touches on the use of natural compounds and the lack of studies due to funding issues.

      community questions for the pyrilutamide users here

      in Treatment  7 upvotes 2 years ago
      The conversation discusses the storage and use of pyrilutamide for hair loss, where one user advises against keeping it in the freezer as it may crystallize the active compounds.

      community How effective is a 7% MNX 0.1% FNS topical?

      in Product  1 upvotes 2 years ago
      A user discusses their rapidly receding hairline and a prescribed topical solution containing 7% Minoxidil, 0.1% Finasteride, and 3% biotinoyl tripeptide. The solution is a custom compound from their dermatologist, costing $50 for a one-month supply.

      community Genetic testing to determine individualized hairloss treatment?

      in Research/Science  10 upvotes 1 year ago
      A user discusses a company, Roots by Genetic Arts, that offers a genetic test for hair loss to create personalized treatments, and is curious about its legitimacy and the science behind it. The company tests 16 genes related to hair loss and compounds a topical treatment based on the results.

      community Tretinoin every other day? (with daily minoxidil)

      in Minoxidil  3 upvotes 2 months ago
      Using Tretinoin every other day with daily Minoxidil may help with hair regrowth, and some users find it more effective than daily use. There are concerns about irritation and absorption, but small amounts seem to minimize harm.

      community Tretinoin every other day? (with daily minoxidil)

      in Minoxidil  1 upvotes 2 months ago
      The user is considering using Tretinoin every other day alongside daily Minoxidil to manage hair loss and is concerned about inconsistent absorption affecting regrowth. They have noticed a significant reduction in shedding but are unsure if it's due to Tretinoin or the end of the Minoxidil/finasteride shedding phase.

      community Began An Intensive Protocol but it's now all habit.

      in Hair Systems  2 upvotes 3 years ago
      The user follows an intensive hair loss protocol including dutasteride, biotin, black tea, pumpkin seed oil, peppermint shampoo, rosemary conditioner, mukemame, soy milk, lycopene, garlic, magnesium, chamomile, spicy food, citrus bergamot, zinc, multivitamins, kefir, and Greek yogurt. They plan to alternate between pumpkin seed oil and safflower oil and will share before and after pictures.

      community Minoxidil vs Minoxidil + Tretinoin vs Minoxidil + LCLT

      in Minoxidil  11 upvotes 4 years ago
      The conversation is about comparing the effectiveness of Minoxidil alone versus Minoxidil combined with other substances like Tretinoin, LCLT, Procapil, Aminexil, and Capixyl for hair growth. One user did not understand the terms used.