New product Tomorrowlabs HSF targets hairloss through HIF pathway indirectly by removing scalp iron. Minoxidil and Stemoxydine also relate to HIF pathway.
The conversation discusses the potential of a new hairloss drug, CB-03-01, with users sharing their experiences and seeking advice on dosages and application methods. One user mentions using topical finasteride, minoxidil, dermarolling, and a clean diet for hair maintenance but is interested in CB-03-01 due to side effects from finasteride.
Pyrilutamide, a potential hairloss treatment that is currently in development and may be available soon; an androgen receptor degrader which is also being developed as a potential treatment for hairloss; and the comparison between Pyrilutamide, finasteride, minoxidil, and RU58841.
A user shared a 6-month update on hair regrowth using Minoxidil 5% liquid twice daily and Finasteride 1mg once daily, along with weekly use of a 1mm Derma roller for 5 weeks. They are pleased with the fuller hair and plan to continue Minoxidil but may temporarily stop Finasteride when trying for a baby.
The user reports regrowth after 5 months using Minoxidil, finasteride, microneedling with a derma stamp, Nizoral shampoo, multivitamins, and biotin, and has shared progress pictures. They apply treatments daily, microneedle twice a week, and exercise regularly, noting an improvement in their mental well-being.
Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.
Kintor Pharma completed enrolling subjects for a Phase III trial of KX-826 for male hairloss treatment. The trial includes a 24-week treatment period and a 4-week safety follow-up, with results expected in about 6-7 months.
The post and conversation discuss Verteporfin's potential as a hairloss treatment. It's shown promise in regrowing hair after transplants and might be effective with microneedling.
The conversation discusses whether it's better to start hairloss treatment with finasteride or dutasteride. Opinions vary, but many suggest starting with finasteride due to its shorter half-life and easier management of side effects, while others argue dutasteride is more effective and has fewer side effects.
Evaluating the effectiveness of taking oral minoxidil as a hairloss treatment, in comparison to finasteride and topical minoxidil; discussing potential side effects of using oral minoxidil.
Hairloss discussion includes finasteride intolerance and questioning if Pyrilutamide is an alternative. Pyrilutamide not commercially available, but may be tolerable if approved since it's not a 5aR inhibitor.
HMI-115, a potential treatment for hairloss that has been reported to produce significant regrowth in bald areas. It is the closest thing to a cure currently available and has raised hope that it could make hair transplants obsolete.
Addressing hairloss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.
The conversation is about a user's 17-month progress in treating hairloss using finasteride, minoxidil, occasional 0.5mm microneedling, and Nizoral. The user reports significant hairline recovery and aims to achieve a pre-hairlosshairline within the next 6 months.
The conversation discusses using a low dose of topical finasteride to achieve hair benefits with minimal systemic exposure. Users share experiences and opinions on dosing, systemic buildup, and side effects of both topical and oral finasteride.
The conversation discusses microneedling techniques and the use of Minoxidil, copper peptides, EGF, FGF, ceramides, and hydration serums to enhance hair growth. It explores optimizing scalp conditions and the potential benefits of various compounds in conjunction with microneedling.
The conversation discusses the effectiveness of commercial Low-Level Laser Therapy (LLLT) devices for hair growth, suggesting they are underpowered compared to the ideal energy output shown in medical research. A user plans to build a custom helmet that meets the required specifications for effective treatment.
A 33-year-old man using finasteride, minoxidil, thickening shampoo, conditioner, and Nizoral noticed peach fuzz after a month and is hopeful for regrowth. Others shared mixed experiences, with some seeing further growth and others not.
The user shared a one-year progress of hair regrowth using topical minoxidil and dutasteride, along with microneedling and scalp massages. They experienced significant hair growth without side effects.
A user discusses their struggle with female pattern baldness, mentioning that Minoxidil helped initially but their hair health declined after stopping a specific diet. They seek advice on managing oily, brittle hair and mention using an egg yolk and olive oil mixture as a temporary solution.
A user shared their experience with a dermatologist's special minoxidil formula containing vitamin E, pantenol, rosemary, and finasteride, which improved their hairloss better than commercial minoxidil. Another user confirmed that the presence of finasteride in the formula is a significant difference.
The conversation discusses whether to try dutasteride for hairloss if finasteride had no effect. Users suggest dutasteride might be more effective as it is stronger and blocks more types of DHT.
The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hairloss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.
A 21 year old man who had a hair transplant 8 months prior and is now more confident due to the results, as well as taking finasteride 3x per week, minoxidil topically and orally, and microneedling; it also includes advice from others on how to further improve his results.
A user traveled to Turkey for a 5000-graft FUE hair transplant at ASMED Clinic with Dr. Koray Erdogan. They used finasteride before and after the surgery and shared detailed experiences, costs, and recovery tips.
A user found that scalp itch might be linked to inflammation rather than DHT alone and noticed hair improvement with certain cancer drugs. They also discovered that black seed oil relieved their scalp itch and are experimenting with a mix of essential oils for dry scalp, questioning if oils affect minoxidil absorption.
A user is making a 2-Deoxy-D-ribose solution and asks if it can be put into an oil instead of a gel, considering adding hydrocortisone and retinoic acid. They seek advice on the best carrier oil for hair growth.
A user who reported positive results from using 1.0mg Finasteride daily and 1.5mm Microneedling every two weeks for eight months, as well as advice about adding Minoxidil to further improve the regrowth process.
Diffuse thinners find shopping challenging due to harsh overhead lighting, but H&M's side lighting in fitting rooms is more flattering. Many users humorously suggest banning overhead lighting to improve the shopping experience.