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      community GT20029 phase II results release date?

      in Research/Science  16 upvotes 1 year ago
      The conversation is about the anticipated release date of phase II results for a hair loss treatment called GT20029 and the cautious optimism surrounding it due to past disappointments with similar treatments. Users expect an update in the next few months.

      community Experiences with Annurmets Hair?

      in Product  6 upvotes 3 years ago
      User asks about Annurmets Hair product, high in Procyanidin B2 for hair regrowth. Product is expensive and ordered from Italy.

      community Brief update clascoterone phase 3 - Breezula

      in Research/Science  4 upvotes 10 months ago
      Cosmo Pharmaceuticals has enrolled about 850 out of 1400 patients for their phase 3 clinical trials of clascoterone (Breezula) and claims to be on schedule. The conversation is about hair loss treatments.

      community Group Buy for MR antagonist finerenone

      in Product  11 upvotes 1 year ago
      User discusses group buy for finerenone, a third-gen mineralocorticoid antagonist for hair loss treatment. Finerenone inhibits TGFb, NOX, and ROS, and improves renal and cardiac function; topical dose should be no more than 10mg per day.

      community Kintor Pharmaceutical Announces AR-PROTAC (GT20029) Approved for Acne and Androgenic Alopecia Clinical Trials in China

      in Technology  14 upvotes 3 years ago
      The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

      community When is GT20029 going to come out?

      in Research/Science  38 upvotes 5 months ago
      The conversation discusses the anticipation and skepticism around the release of GT20029 for hair loss treatment. The original poster has been using Finasteride and Minoxidil but is hopeful for GT20029, while others express doubts about its timely release and suggest alternatives like KX826 and hair transplants.

      community Is it possible that dutasteride won’t make you depressedd if finasteride did?

      in Chat  16 upvotes 9 months ago
      The conversation discusses whether dutasteride might cause less depression than finasteride for hair loss treatment, with some users suggesting it could due to different mechanisms of action or molecular size, while others express skepticism or share personal experiences with these medications.

      community Fluridi + minoxidil (no finasteride?)

      in Treatment  5 upvotes 11 months ago
      The user is using minoxidil and recently started fluridil for mild hair loss and is questioning if this treatment is sufficient without finasteride. They have finasteride available but prefer not to use it.

      community Results of Procyanidin B2 in clinical studies

      in Treatment  13 upvotes 4 years ago
      Procyanidin B2, a compound derived from Annurca apples, as a potential treatment for pattern hair loss. Several clinical studies were mentioned, which found that procyanidin B2 could increase hair growth, density, and keratin content. Other treatments such as Minoxidil, Finasteride, and RU58841 were not discussed.

      community Latanoprost from the gray market?

      in Chat  4 upvotes 8 months ago
      The conversation discusses sourcing pure latanoprost from the gray market for research and making a homemade solution. Concerns about potential dangers and experiences with this method are raised.

      community Saw Palmetto/Pumkin seed gives basically same results as Fin

      in Treatment 5 months ago
      A user reported that Procerin, containing Saw Palmetto and Pumpkin seed oil, provided similar hair thickening results as finasteride but with milder side effects. They experienced reduced libido and watery ejaculations but are adjusting the dose to minimize these effects.

      community If RU58841 is such an effective anti androgen

      in Research/Science  46 upvotes 1 year ago
      RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.

      community Starting Pyrilutimide 5% Update

      in Treatment  1 upvotes 1 year ago
      The user started using Pyrilutamide 5% for hair loss and has not experienced side effects after two days. They previously had side effects from Fluridil and topical Minoxidil 5%, and their hair continued thinning with topical Spironolactone.

      community Dutasteride RAISES LIBIDO!

      by Alessandro in Treatments  222 upvotes 8 months ago
      Dutasteride can significantly increase libido, more so than finasteride. Users reported higher libido when switching from finasteride to dutasteride.

      community What ever happened to pyrilutamide?

      in Technology  47 upvotes 1 year ago
      Pyrilutamide, a potentially effective hair loss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.

      community Tressless When They See Verteporfin Results

      in Transplants  182 upvotes 1 year ago
      The conversation discusses the potential of Verteporfin, an FDA-approved drug, for hair loss treatment, particularly in combination with microneedling or PRP. Users express hope and curiosity about its application, while some remain cautious due to the need for more extensive testing.

      community So... any chinese suppliers for real pyri?

      in Research/Science  6 upvotes 7 months ago
      The conversation discusses sourcing pyrilutamide from China for hair loss treatment, highlighting its potency compared to other AR antagonists like bicalutamide and RU58841. The user expresses interest in trying pyrilutamide despite mixed results in clinical trials.

      community First 3 pics are at 6 months .5 mg fin daily, last 3 are 13 months

      in Progress Pictures  75 upvotes 1 year ago
      The user experienced improved hair at 6 months using 0.5 mg finasteride daily but noticed more scalp visibility and potential hair loss at 13 months, questioning if this was due to shedding or the treatment not working. Some respondents suggested the possibility of a shed or scalp inflammation, while others observed improvements or advised checking for underlying scalp conditions.