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      community Is regrowth on an androgen receptor blocker possible?

      in Chat  11 upvotes 6 months ago
      RU and Pyri block androgen receptors to prevent hair loss but may also hinder hair regrowth since they prevent testosterone, which can stimulate hair growth, from binding to these receptors. The user is questioning if this understanding is correct.

      community Just started RU a month ago after being on fin and min for almost 3 years. Progress so far: My temples were pretty bare before this. Really hoping at least some of these become terminal.

      in Is this regrowth?  396 upvotes 6 months ago
      A user started using RU58841 a month ago after using finasteride and minoxidil for nearly three years, hoping for hair regrowth at the temples. Other users suggest vitamin B supplements and microneedling to improve hair thickness, and one mentions the possibility of a hair transplant for the temples.

      community Kintor does not have abandoned KX-826 - ANNUAL RESULTS 2023

      in Product  8 upvotes 7 months ago
      The conversation discusses disappointment with the hair loss treatment KX-826 but notes that the company Kintor is still focused on developing and commercializing it, as stated in their 2023 annual report. The user questions the effectiveness of KX-826 in comparison to minoxidil's role in improving hair thickness and appearance.

      community 6 months into Dutasteride and my hair is way worse than before

      in Finasteride/Dutasteride  73 upvotes 7 months ago
      After six months on Dutasteride, the user's hair is worse than before, despite previously trying finasteride and RU/Fluridil without success. Some suggest continuing Dutasteride and adding progress photos, while others share their positive experiences or advise sticking to one treatment for at least a year.

      community TRT. Pyrilutamide. Ru58841. Help

      in Treatment  3 upvotes 7 months ago
      A 30-year-old man experienced significant hair loss after starting testosterone replacement therapy (TRT), which did not improve with daily finasteride and minoxidil. He is considering restarting TRT and is seeking advice on using pyrilutamide or RU58841 to prevent further hair loss.

      community Is there any new drug that looks promising ?

      in Research/Science  25 upvotes 8 months ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

      community What to take from the Actifolic?

      in Finasteride/Dutasteride  1 upvotes 9 months ago
      The user is considering starting Minoxidil and is looking for a topical solution to combine with it. They are confused about which product to prioritize among options like RU58841, Pyrilutamide, FinaTopic, and DutaTopic.

      community Finasteride, minoxidil and pyrilutamide

      in Progress Pictures  79 upvotes 9 months ago
      The user tried minoxidil 5% for 3 years with little improvement, then switched to a 15% minoxidil with 0.1% finasteride solution once daily and started using pyrilutamide, resulting in significant hair regrowth over time. They are considering a hair transplant but are continuing with topical treatments to maximize hair growth first.

      community found my progress pictures on a scam account

      in Progress Pictures  58 upvotes 10 months ago
      A user discovered their hair regrowth progress pictures were used in a scam promoting a fake "elixir." The user clarified that their actual results came from using finasteride and minoxidil for three months.

      community 2 months update, experiencing massive gains

      in Progress Pictures  444 upvotes 10 months ago
      A user reports significant hair regrowth after 2 months using Minoxidil, Finasteride, oiling, derma rolling, and taking multivitamins, omega 3, and vitamin D. Some users discuss the frequency of derma rolling, with varying practices ranging from once every two weeks to four times a week.

      community Y'all ever watch older movies?

      in Chat  63 upvotes 11 months ago
      The conversation reflects on how hair loss was portrayed in older movies as a natural part of aging, contrasting with today's media where balding is less visible due to treatments like finasteride and hair transplants. Participants also discuss the difference in societal attitudes towards hair loss and appearance in past generations compared to the present.

      community Pyrilutamide phase III clinical trial results released

      in Research/Science  31 upvotes 11 months ago
      Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.

      community KX-826 Phase 3 Failed. Sorry guys...

      in Research/Science  49 upvotes 11 months ago
      The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.

      community [Serious] Experience with grey-market KX-826 (Pyrilutamide)

      in Research/Science  2 upvotes 1 year ago
      The user experienced reduced hair loss using grey-market KX-826 alongside Minoxidil foam, achieving better results with Minoxidil liquid but restricted to foam due to an allergy. Initial side effects included shortness of breath, racing heart, and dizziness, which subsided after the first week.

      community There is news from pyrilutamide?

      in Product  32 upvotes 1 year ago
      The discussion is about a hair loss drug called pyrilutamide. Users discuss its efficacy, safety, and expected market release around 2025-2026, with some expressing concerns about the authenticity of current market offerings.

      community I have been applying undiluted, pure 100% peppermint oil to my scalp, 2.5ml a day as an experiment

      in Treatment  92 upvotes 1 year ago
      A user is experimenting with applying undiluted peppermint oil to their scalp daily to stimulate hair growth, based on a rat study where peppermint oil outperformed minoxidil. The user reports immediate hair thickening and increased scalp blood flow, while others in the conversation express skepticism, humor, and concern about the undiluted application.

      community It's not just about your hair, it's also about YOU!

      in Chat  73 upvotes 1 year ago
      The user has been on Finasteride and oral Minoxidil for hair loss and experienced minimal side effects. They suggest that a healthy lifestyle, including good sleep, exercise, diet, skincare, and mental health care, may help reduce the perceived side effects of Finasteride, although another user disagrees, emphasizing that side effects can vary and may not be mitigated by lifestyle alone.