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      community Androgen degraders for hair loss

      in Research/Science  61 upvotes 4 months ago
      The conversation discusses androgen receptor degraders for hair loss, highlighting their potential advantages over traditional AR blockers like RU58841 and pyrilutamide. Concerns about the safety and cost of these treatments are also mentioned.
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      community Clascoterone (Winlevi) now approved in Canada

      in Product  13 upvotes 1 year ago
      The conversation is about the approval of Clascoterone (Winlevi) in Canada for hair loss treatment. One user expressed skepticism about its effectiveness due to low concentration.

      community discouraged about pyrilutamide

      in Research/Science  11 upvotes 2 years ago
      Discouragement regarding Pyrilutamide, a drug in development for hair loss, and the potential side effects of Finasteride. People discussed anecdotal experiences with Pyrilutamide as well as suggestions to wait out Phase 3 trials before making any conclusions.

      community Anybody interested in a new seller option for hair loss topicals?

      in Chat  6 upvotes 2 years ago
      A user with hair loss is considering starting a business selling hair loss treatments, including RU58841, low-dose topical finasteride with optional minoxidil and tretinoin, and topical melatonin. They are also contemplating offering Pyrilutamide and other unique topicals, seeking feedback on interest and suggestions for their potential store.

      community Brutal Hair loss At 19: Help+Treatment Questions

      in Chat  6 upvotes 3 years ago
      A 19-year-old experiencing hair loss since 17 uses finasteride, minoxidil, dermaroller, ketoconazole shampoo, and oral castor oil, but sees little improvement. They seek advice on adding an anti-androgen, considering alfatradiol.

      community Kintor Pharmaceutical Announces AR-PROTAC (GT20029) Approved for Acne and Androgenic Alopecia Clinical Trials in China

      in Technology  14 upvotes 3 years ago
      The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

      community Any user of eucapil who got sides ?

      in Treatment  8 upvotes 4 years ago
      User wants to try Eucapil for hair loss but experienced side effects from finasteride. Seeks feedback on Eucapil's potential side effects.

      community Fluridil vs Breezula?

      in Treatment  16 upvotes 4 years ago
      Comparing two upcoming topical hair loss treatments, Fluridil and Breezula, to determine which is most effective for treating hair loss, taking into consideration factors such as price, side effects, potential for hair growth, convenience of application, smell, greasiness, and styling after use.

      community Why haven’t we seen anything about this

      in Research/Science  19 upvotes 4 years ago
      A double blind, placebo-controlled study that looked into the potential effectiveness of topical fluridil for treating male androgenetic alopecia, showing increased anagen to telogen ratios with no reported side effects on libido or sexual performance.

      community SETIPIPRANT PGE2 GROUP BUY AND PIONEERING HAIR GROWTH

       7 upvotes 8 years ago
      The conversation is about a user seeking help with hair regrowth treatments, specifically mentioning Setipiprant, Minoxidil, Finasteride, and RU58841. The user is trying to contact forum members for guidance on making and using these treatments.

      community Q1/Q2 Exciting times ahead - hope!

      in Research/Science  17 upvotes 1 month ago
      The conversation discusses various hair loss treatments, including Breezula, KX826, and PP405, with mixed opinions on their effectiveness compared to finasteride and minoxidil. Some users express skepticism about the new treatments, while others remain hopeful about future developments.
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      community Topical bicalutamide vs ru58841

      in Female  1 upvotes 5 months ago
      A user is seeking advice on making a topical bicalutamide solution as an alternative to RU58841 for hair loss, while already using dutasteride and minoxidil. They are considering crushing bicalutamide pills and adding them to their minoxidil.

      community Am I balding? Should I just shave it off?(M86)

      in Satire  116 upvotes 8 months ago
      A user humorously questions if they should shave their head due to hair loss, mentioning Ronald Reagan's impressive hair genetics. Replies include jokes and comments about jealousy and distrust towards older individuals with full heads of hair.

      community Questions about alfatradiol logistics

      in Treatment  4 upvotes 1 year ago
      The user is seeking help with using Ell-Cranell for hair loss treatment. They are unsure about the correct application method and dosage. They also inquire about combining microneedling with topical alfatradiol and question a study that referred to alfatradiol as a hair growth inhibitor in male mice.

      community Andreas Townsend takes 15mg Fin 2x per day 🤣

      in Satire  796 upvotes 1 year ago
      Andreas Townsend's hair growth, likely due to a combination of finasteride and minoxidil treatments, as well as possibly a hair transplant. People have been discussing the efficacy of these treatments in achieving Townsend's level of hair growth.

      community [Research/Science] What's the General Consensus On Pyrilutamide So Far?

      in Research/Science  8 upvotes 2 years ago
      Pyrilutamide is considered to work for hair loss but less effectively than expected, similar to RU58841, and may cause side effects like chest tightness and sexual issues. It's unclear if it's suitable for diffuse thinners, and one user cannot use minoxidil or finasteride due to side effects and personal circumstances.

      community All Drugs in Clinical Trials in 2023

      in Research/Science  71 upvotes 2 years ago
      12 companies having drugs or therapies in clinical trials during 2023, with various molecules and phases of trial; the probability that some may fail; and progress being made in the field.

      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  450 upvotes 2 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community pyrilutamide any results so far?

      in Treatment  44 upvotes 2 years ago
      The hair loss treatment Pyrilutamide and whether it has had any results for users. Martinsahara is planning to buy some soon.