The user has been using finasteride, dutasteride, and RU58841 for hairloss without success and feels extremely uncomfortable with their appearance, including being bald and short. They express deep unhappiness and social isolation. Suggestions from others include adopting stoicism, focusing on personal development, considering a hair system, improving fashion, working out, and seeking therapy for mental health.
The user experienced worse hair after removing a wig system and has been using Hairband 82 Comfort Flex, Hair Max supplements, dermarolling, and a scalp massager for 4 months without clear results. They are hesitant to use Minoxidil due to shedding concerns and avoid finasteride due to side effects, preferring Saw Palmetto instead.
The conversation discusses the importance of taking vitamin D with food for better absorption and its potential role in hairloss. Some users also suggest taking vitamin D with K2, getting sunlight, and using finasteride for hairloss treatment.
User tried dutasteride, topical finasteride, oral minox, dermawounding, saw palmetto, pumpkin seed oil, and ketacozonole for hairloss. Improvement was temporary, now trying RU58841 and seeking help.
The conversation is about the availability of WINLEVI, a hairloss treatment, and the possibility of getting it compounded. The user is seeking information on when they can obtain the treatment.
The conversation discusses GT20029, a new topical drug for hairloss and acne without notable side effects, which has been accepted for investigational use in China. Some users express skepticism about the legitimacy of the company and the potential for other drugs like RU58841 to be developed due to patent expiration and lack of profitability.
The potential health risks associated with long-term use of finasteride and dutasteride, with some responses pointing out the low quality of the journal that published the review article as well as highlighting other alternatives such as keto or minoxidil, and RU58841.
The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.
The conversation discusses the hairloss treatment Breezula by Cassiopea, which had a successful Phase II trial and is expected to start Phase III by the end of the year. Users are curious about the timeline for availability and note that it performs slightly better than finasteride at 6 months, slightly worse at 12 months, with the benefit of having no side effects.
Pumpkin seed oil is discussed as a potential treatment for hairloss, but the study cited is criticized for using a product with multiple ingredients, making it unclear if pumpkin seed oil is effective. The conversation concludes with skepticism about the study's validity and mentions that pumpkin seeds might help with DHT blocking.
Vitamin E was discussed as a treatment for hair shedding, with a specific form mentioned. A user shared a link to a study and started taking the Vitamin E variants used.
A double-blind clinical study that found ingestion of tocotrienols resulted in a 34.5% increase in hair regrowth compared to the placebo group, and discussion about potential side effects and cost of supplementation with vitamin E pills. The conversation noted that it may be more effective than commonly used treatments like minoxidil and finasteride.
A 23-year-old experiencing hairloss tried olive oil, coconut oil, and hair growth shampoos without success. They are seeking advice on whether to start treatments like Minoxidil, finasteride, or RU58841.
A 21-year-old male with a thyroid condition noticed his hair thinning uniformly without a receding hairline. He is considering using a 5ARI to prevent further baldness if he starts TRT.
Hair follicles usually go dormant rather than die, and treatments like finasteride, minoxidil, and hormone therapy can sometimes reactivate them, though results vary. Complete regrowth is rare, especially in long-term bald areas, but some individuals see significant improvement with these treatments.
A 20-year-old is dealing with male pattern baldness and considering finasteride despite concerns about side effects. Users recommend treatments like minoxidil, dutasteride, and lifestyle changes, stressing early intervention.
The user has used minoxidil for five years and added microneedling for four weeks without seeing results. They are considering a hair transplant but are advised that hairloss will persist without a DHT blocker.
A 25-year-old is frustrated with hairloss and inability to grow facial hair despite using oral finasteride and minoxidil for over a year. Suggestions include trying topical treatments, considering a hair system, or seeking professional help for mental health.
Ketoconazole shampoo helps reduce hair shedding and improve thickness for some, but can cause dryness or irritation. Its effectiveness compared to finasteride or minoxidil varies among users.
The user experienced significant hair thickening after nearly 5 months on 5 mg oral minoxidil and over 10 years on 1 mg finasteride, with no side effects. They are considering a hair transplant for the hairline but are pleased with the current results.
Some men have strong balding genetics that treatments like Dutasteride, Minoxidil, or Finasteride may not fully address. Early intervention is believed to help, but many accept hairloss without treatment.
Finasteride improved hair appearance over seven years with no major side effects. Users discussed finasteride, minoxidil, and supplements like beta carotene and astaxanthin for hairloss treatment.
Skepticism about hairloss research motivations, suggesting financial interests hinder finding a cure. Mentions treatments like minoxidil, finasteride, and dutasteride, but notes they are not cures.
GT20029 and KX826 are promising hairloss treatments, with GT20029 increasing hair count and KX826 showing significant results. KX826 may be a good alternative for those who can't use finasteride or dutasteride, though results vary.
PP405 is considered a promising potential cure for hairloss, with phase 2 trial results expected in February 2025. Hair cloning is also discussed as a potential ultimate solution, despite significant scientific challenges.
The user stopped finasteride for three months to try for a baby but continued using minoxidil and micro-needling. They are concerned about hair shedding and plan to resume finasteride after the baby is born.