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Minoxidil may cause skin aging effects like wrinkles and dark circles, but evidence is mixed. Alternatives like dermarolling and retinol are suggested.

Chinese company gets green light for Pyrilutamide Phase II trial for androgenetic alopecia. Androgen receptors downregulate in androgen deficient environments.

A user used oral finasteride and minoxidil for hair loss, seeing new hair growth under a microscope but no visible change. Commenters debated if the growth was real hair or fibers, and the user will update every 90 days.

Dutasteride at 2.5 mg/day reduces scalp DHT by 80%, while 0.5 mg/day reduces it by 50%, with minimal difference in side effects. Users often combine it with finasteride, RU58841, and minoxidil for better hair loss management, though side effects like dry skin and pimples are noted.

Ketoconazole shampoo helps reduce hair shedding and improve thickness for some, but can cause dryness or irritation. Its effectiveness compared to finasteride or minoxidil varies among users.

The user experienced increased hair miniaturization and shedding despite using finasteride, topical minoxidil, microneedling, and other treatments. They are considering more aggressive treatments or a hair system if no improvement occurs by the end of 2025.

A user experimented with applying hot water to their scalp to potentially stimulate hair growth, noting reduced dandruff but uncertain hair loss results. They started this method due to side effects from minoxidil and are considering taking a break to observe changes.

A 29-year-old male shares his 3-month hair regrowth progress using finasteride, minoxidil, and microneedling, reporting no side effects and light initial shedding. He is encouraged by the results and plans to continue the treatment.

Increased coffee intake might be linked to hair shedding, but the cause is unclear. The user is on finasteride and has increased water intake, possibly affecting electrolyte balance.

The user has been using topical minoxidil and finasteride for nearly four months, along with derma rolling and Nizoral, and is seeing noticeable hair regrowth and thickening, especially around the temples and crown. They are considering continuing the treatment and possibly trying oral finasteride, but are cautious due to a history of depression.

A user discusses their current hair loss treatment of topical minoxidil, tretinoin, and dermarolling, and considers adding topical spironolactone due to concerns about finasteride's mental side effects. Other users advise against topical spironolactone, citing ineffectiveness and unpleasant smell.

The user reported significant hair regrowth after 2.5 months using 5% minoxidil, later switching to 10% minoxidil, finasteride, and oral minoxidil. The combination of topical and oral treatments showed impressive progress with minimal side effects.

Follicopeptide (FOL005) by Coegin Pharma will launch as a cosmetic hair growth treatment by Q2 2025, showing similar efficacy to finasteride. Users discuss the benefits and skepticism of releasing hair loss treatments as cosmetics rather than drugs.

Dutasteride is unlikely to worsen hair loss; shedding is often temporary. Other factors like inconsistent use, placebo effect, or additional treatments may influence perceived results.

A user is making a 2-Deoxy-D-ribose solution and asks if it can be put into an oil instead of a gel, considering adding hydrocortisone and retinoic acid. They seek advice on the best carrier oil for hair growth.

Glycosaminoglycans are important for hair growth, and combining minoxidil with tretinoin and Biopeptide-CL may enhance hair growth by boosting glycosaminoglycan levels and improving the hair follicle environment. Users discussed the potential effectiveness and future of these treatments.

The user is using a combination of RU58841, Stemoxydine, RevivHair Serum, hair growth oil, topical Minoxidil, Alfatradiol, oral Minoxidil, and Finasteride to treat hair loss. They report no side effects from oral Minoxidil and Finasteride after 7 months of use.

Finasteride is not a miracle drug; results vary widely, with only 2/5 getting good results. Combining treatments like minoxidil and finasteride may help, but expectations should remain low.

Dutasteride is generally considered more effective than finasteride for hair regrowth and thickening, despite some negative anecdotal reports. Users report thicker hair and better skin with dutasteride, and some believe negative reviews are due to advanced alopecia or impatience with the shedding process.

A 16-year-old diagnosed with male pattern baldness (MPB) was prescribed hair vitamins, vitamin D, a non-ketoconazole shampoo, and redenysl + serum, with a suggestion for GFC or IHRF treatments. Some users recommended minoxidil, ketoconazole, and derma stamping, while others advised against certain treatments until the age of 18.

Users discuss their positive experiences with finasteride for hair loss, mentioning halted hair loss, hair regrowth, and improved self-esteem. Some express satisfaction in taking action against baldness, while others note increased libido and energy.

A user hopes to regrow hair using a routine of Min/fin solution twice daily, dermarolling twice weekly, multivitamins daily, and biotin twice daily. Another user doubts the effectiveness of biotin and multivitamins.

The conversation discusses the potential benefits of finasteride (Fin) for lowering cholesterol and reducing cardiovascular disease risk, with users sharing personal experiences and opinions on the medication's effects on health and hair loss. Some users report positive changes in cholesterol levels after taking finasteride, while others are skeptical or joke about its effects.

Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.

The conversation discusses whether finasteride would still be necessary if Verteporfin becomes a successful hair loss treatment. It also explores the sensitivity of transplanted hair to DHT and the potential for off-label use of Verteporfin post hair transplant.

The conversation is about a user considering the use of Ketoconazole 2% shampoo before showing signs of male pattern baldness (MPB) to potentially delay its onset, inspired by a YouTuber who uses the shampoo to reduce scalp DHT levels. The user's interest in this preventative measure stems from a family history of MPB.

The post discusses the theory that melatonin could reverse grey hair by regulating certain enzymes. However, users who have taken melatonin reported no effect on preventing or reversing grey hair.

The post discusses potential links between low vitamin D levels and hair loss, and how correcting this might impact the effectiveness of Minoxidil and Finasteride treatments. The responses vary, with some suggesting that vitamin D deficiency would cause overall scalp hair loss, while others believe it would first affect the most sensitive areas.

The user has been using minoxidil for years without success, but after adding DUT (dutasteride) to their routine, they have seen progress in their hair growth.

The conversation is about scalp massages for hair loss, with skepticism from users who suggest using finasteride, dutasteride, and minoxidil instead. Users report no success with scalp massages and consider it a scam.