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      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  6 upvotes 3 months ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community Looking for the new RU58841 source in EU

      in Product 5 months ago
      The user is seeking a new source for RU58841 in the EU after their previous supplier stopped selling it. They mention considering Anagen, Actifolic, Minoxidilmax, and rudirect, and ask for advice on shipping within the EU and product quality, while also mentioning their current hair loss treatment involves mixing RU with Stemoxydine and Alfatradiol.

      community Fluridil/topilutamide experince

      in Treatment  3 upvotes 6 months ago
      A user is trying fluridil/topilutamide for hair loss and experiencing side effects like pain in the testicles and genital discomfort. They previously had adverse effects with finasteride, dutasteride, and RU58841, and are considering other treatments like topical dutasteride and spironolactone for maintenance before a hair transplant.

      community 6 months aggressive treatment for hair loss

      in Progress Pictures  117 upvotes 6 months ago
      The user shared a 6-month aggressive hair loss treatment progress, using oral minoxidil, finasteride/minoxidil topical, dutasteride, derma stamping, Nizoral, and daily Cialis, which notably improved regrowth. Commenters observed significant improvement, with one noting a change from a Norwood 5 to a Norwood 1 in hair loss classification.

      community Started fighting hair loss at 55, it's working.

      in Update  22 upvotes 8 months ago
      A user started treating hair loss at 55 using 0.5 mg finasteride, 5% minoxidil every second day, and microneedling. They saw noticeable improvement, especially in the front and a previously smooth bald spot.

      community Been following this guy for 2 months

      in Is this regrowth?  147 upvotes 9 months ago
      A person on TikTok has been using finasteride, minoxidil, scalp massage, rosemary oil, and microneedling for hair loss treatment for 6 months, and recently switched from oral to topical finasteride. Some believe finasteride and minoxidil are the most effective treatments, while opinions on switching to topical finasteride are mixed.

      community Ru with gloves because of Systemic absorption?

      in Research/Science  9 upvotes 9 months ago
      The conversation is about whether to use gloves when applying 5% RU58841 to avoid systemic absorption and if washing hands with water is sufficient. Users question the concern, noting it is applied to the scalp.

      community Journey and recommendation for Bay Area doctor

      in Treatment  2 upvotes 9 months ago
      The user has tried various hair loss treatments including minoxidil, finasteride, and others, experiencing side effects and is seeking recommendations for a knowledgeable doctor in the California Bay Area. They had a negative experience with one doctor and are considering a hair transplant but want to avoid further side effects.

      community 1 year in - any progress on my crown?

      in Is this regrowth?  14 upvotes 11 months ago
      The user tried various hair loss treatments for a year, initially using Hims foam min, Ketoconazole, dermarolling/microneedling, Biotin, Collagen, Caster and rosemary oil, and a multivitamin. From June, they switched to Keeps topical fin and min gel, Ketoconazole, dermarolling/microneedling, collagen, Caster and rosemary oil, and a multivitamin, and noticed hair thickening, especially on the front hairline.

      community How many Dut pills does it take to have Franz Kafka's hairline?

      in Satire  48 upvotes 1 year ago
      The post and conversation discuss hair loss treatments and the uncertainty of their results. Some users suggest that artificial hair systems might be the best solution, while others express preference for maintaining a mature hairline rather than aiming for a youthful one.

      community Just over 4 months in. Am I seeing things?

      in Is this regrowth?  37 upvotes 1 year ago
      The user reports potential hair regrowth after using finasteride nightly, minoxidil twice daily, occasional microneedling, and vitamin supplements, and is considering RU58841 in the future. Replies suggest they are seeing improvement.

      community The guy should have been on fin

      in Satire  191 upvotes 1 year ago
      Hair loss treatments mentioned: finasteride, dutasteride, and hair transplant. Misunderstandings in conversation involve wordplay on "bill," "check," and "to pay" sounding like names and phrases.

      community M23 , on finaestride and minoxidil for 4.8 months

      in Progress Pictures 1 year ago
      . This conversation is about a user's progress while using minoxidil and finasteride to treat hair loss, with emphasis on taking oral finasteride at night before bed for optimal results. They also discuss the brand of medication being used (Morr F 5%) and the importance of taking a generic version of the same drug.

      community 2nd day on pyrilutamide - what I noticed so far

      in Treatment  7 upvotes 1 year ago
      The user started using a hair loss treatment called pyrilutamide and experienced mild chest discomfort and tightness, similar to previous side effects from RU58841. They plan to reduce the dosage due to these side effects and will provide an update on the results in 1-2 months.

      community GT20029. Kintor Pharma’s Product

      in Research/Science  13 upvotes 1 year ago
      The conversation discusses GT20029, a compound by Kintor Pharma that degrades androgen receptors and is in trials, with potential as a hair loss cure. Another promising treatment mentioned is an antibody that blocks prolactin and has shown positive results in macaques.

      community two pics, one in August and other in November… it has been almost 4 months just on minoxidil 5% spray, noticed an improvement in hair quality and helped me stop shedding hair which I experienced before treatment👌🏼

      in Progress Pictures  343 upvotes 1 year ago
      This user experienced an improvement in hair quality and stopped shedding by using Minoxidil 5% spray twice a day for 4 months. Other users encouraged the use of finasteride to maintain the results, as it is the only treatment that addresses the underlying cause of hair loss.

      community My experience with Pyrilutamide

      in Update  43 upvotes 1 year ago
      Two different experiences of using Pyrilutamide, a hair loss treatment, which caused headaches that took around a week to subside in both cases. Other users offered insight into their own experiences with the treatment or suggested alternate treatments such as RU58841 and Minoxidil.

      community Minoxidil alternative with a week long half-life? Why isn’t it possible?

      in Satire 2 years ago
      This conversation discussed the potential for a hair loss treatment alternative to minoxidil, with many users debating the economic and health implications of such an option. Some suggested that finasteride could be used as an alternative, while others argued that this would ultimately not benefit pharmaceutical companies due to their reliance on planned obsolescence.

      community Why can't you drink caffeine after PRP?

      in Treatment  10 upvotes 2 years ago
      The conversation discusses avoiding caffeine after Platelet-Rich Plasma (PRP) treatment for hair loss because caffeine is a vasoconstrictor, which can reduce blood flow and hinder the healing process that PRP aims to promote.

      community Been on Min and Fin for Years and I am Devastated.

      in Treatment  64 upvotes 2 years ago
      Guyman567 has been using oral finasteride and topical minoxidil for years but continues to experience hair loss and thinning, which has affected his confidence. He has tried various treatments including topical finasteride, microneedling, and vitamins, and is considering a hair transplant but is concerned about ongoing hair loss.

      community A new meta-analysis of 23 studies has confirmed that 5 milligrams a day of oral dutasteride had the highest probability of reducing male hair loss, followed by 5 milligrams a day of oral finasteride, followed by 5 milligrams of oral minoxidil, followed by 1 milligram a day of oral finasteride

      in Research/Science  82 upvotes 2 years ago
      Oral dutasteride (0.5mg) is most effective for male hair loss, followed by oral finasteride (5mg), oral minoxidil (5mg), and oral finasteride (1mg). Different treatments have benefits and side effects, and results don't apply to women's hair loss.