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GlossaryEndothelial Cells

line blood and lymphatic vessels, regulating vascular functions

Endothelial cells form the thin layer of cells lining the interior surface of blood vessels and lymphatic vessels, known as the endothelium. These cells play a crucial role in regulating blood flow, vascular tone, and the exchange of substances between the bloodstream and surrounding tissues. They are also involved in angiogenesis (the formation of new blood vessels) and maintaining vascular homeostasis.

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community New and Interesting HairLoss Studies/Papers/Reviews

TerpsandCaicos in Treatment 41 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Comprehensive Microneedling Guide

throwoveraccount in Microneedling 294 upvotes 2 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community Solving Hair Loss with Research at MIT

ekkolapto1 in Research/Science 594 upvotes 3 months ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community Being Safe on Oral Minoxidil: tl;dr on the literature.

noeyys in Research/Science 49 upvotes 1 month ago

Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

community Long term finasteride users; Did you notice any improvement after 2 years?

SimmaG98 in Finasteride/Dutasteride 14 upvotes 1 year ago

Long term Finasteride users and whether or not they have noticed improvements after two years of use, with other treatments such as Minoxidil and dermarolling also discussed. Some replies suggest that improvement is possible even beyond the two year mark while others caution against believing studies backed by the Post-Finasteride Foundation.

community How do athletes maintain their hair transplants? Or do they not?

bucketGetter89 in Transplants 57 upvotes 1 month ago

Athletes often use finasteride to maintain hair transplants, but some avoid it due to potential hormonal effects. Notable examples include Mo Salah and Conor McGregor, while LeBron James has had multiple procedures with varying success.

community How all hormones affect our hair follicles. Not just DHT. Take a look at this paper. Prolactin, melatonin, cortisol, progesterone, testosterone and more

Combfromhell in Research/Science 126 upvotes 2 years ago

The conversation discusses various factors affecting hair loss, not just DHT, and mentions treatments like Minoxidil, finasteride, and melatonin. Some users report personal experiences with these treatments and hormone tests, while others speculate on the role of hormones like prolactin and cortisol in hair loss.

community Caffiene shampoos left in for 2 minutes show comparable results to Minoxidil, and may work differently than Minoxidil, which can add to your stack, or work for non responders

Sk8rchiq4lyfe in Research/Science 42 upvotes 8 months ago

Caffeine shampoos show comparable results to Minoxidil and may enhance its effects when used together. Caffeine can be detected in the scalp up to 24 hours after a 2-minute application, making it an affordable treatment option.

community The shedding caused by Minoxidil is one of the worst things. 2 months apart each picture

elbarbarojja in Progress Pictures 290 upvotes 5 months ago

The conversation discusses the severe shedding caused by Minoxidil, with users sharing their experiences and outcomes. Some report eventual regrowth, while others see no improvement or worsening hair loss.

community Atherosclerosis as cause of balding and treatment

FlowingPetal in Treatment 61 upvotes 1 year ago

Hair loss may be caused by calcification of capillaries in the scalp, restricting blood flow to hair follicles. A daily treatment regimen including high doses of Vitamins D and K, Magnesium, and Nattokinase could potentially decalcify these capillaries, improving blood flow and hair growth. However, some users warn against excessive Vitamin D intake and emphasize the need for medical consultation.

community What About Phytosterol Alternatives - Rice Bran Oil - Natural DHT Blockers

Ok_Letter_8678 in Research/Science 4 upvotes 9 months ago

The conversation discusses natural DHT blockers like rice bran oil, which may reduce 5α-reductase activity similarly to Minoxidil and Dutasteride. One user argues that finasteride is more reliable and effective than natural alternatives.

community My baby is balding! (Norwood 7)

danceandchance in Satire 1168 upvotes 1 year ago

The conversation is a satirical discussion about a baby with hair loss using adult hair loss treatments like finasteride, minoxidil, and ketoconazole, as well as dermarolling, scalp massages, and plans for PRP sessions. Suggestions include various other treatments and humorous advice, reflecting the satire of the situation.

community How fast do wounds from derma rolling heal in your experience?

MCUFanFicWriter in Microneedling 10 upvotes 7 months ago

The user has been using minoxidil and finasteride for hair loss but is now considering microneedling due to recent hairline regression. Another user reassures that derma rolling causes only slight redness, which usually heals overnight.

community Long Hair DHI Hair Transplant, 2750 grafts.

Capable-Success-7940 in Transplants 457 upvotes 5 months ago

A user shared their experience with a Long Hair DHI Hair Transplant, receiving 2,750 grafts. They plan to continue using Dutasteride and Topical Minoxidil post-surgery.

community 4 months Oral Minoxidil 1.25 mg Daily (33 M)

ediblediety in Progress Pictures 520 upvotes 2 years ago

This user, "ediblediety", has been taking oral minoxidil (1.25 mg daily), keto shampoo and occasional derm-rolling for 4 months to treat their hair loss, and they have experienced a shedding phase after the first few weeks of use. They report improvements in the thickness of their facial and body hair, but note that this may be daunting to women.

community I’ve been on dutesteride and oral minoxidil for two years now and I’ve only lost ground…

flummoxed_pegasus in Treatment 42 upvotes 11 months ago

A user on dutasteride and oral minoxidil for two years reports worsening hair loss and is seeking advice. Suggestions include consulting a professional for underlying causes, acknowledging that treatments don't work for everyone, and considering dosage adjustments or additional treatments.

community Blood test 3 days after finasteride. Is it ok?

EZELDWIN in Finasteride/Dutasteride 3 upvotes 8 months ago

A user asked if taking a blood test 3 days after starting finasteride would affect the results for Estradiol, FSH, SHBG, Progesterone, and DHEA-S. The conversation is about the timing of blood tests after beginning finasteride treatment.

community Oral minoxidil may not be as dangerous as what people say

shouldbestudyingbye in Minoxidil 9 upvotes 4 years ago

The safety of using oral minoxidil to treat hair loss and thinning, with studies showing mild side effects at low doses. It was suggested that people should consult a doctor or dermatologist before taking any type of medication for hair loss.

community Well, I guess this puts the scalp tension theory to bed

LeFroyain in Satire 138 upvotes 3 years ago

Hair loss discussion includes various causes like DHT, blood flow, and skin fibrosis. Treatments mentioned are Minoxidil, Finasteride, and RU58841.

community My slick bald temples ( for about 7-8 years ) FIN MIN KETO MICRONEEDLING 2 months +

DirectorIntelligent1 in Progress Pictures 54 upvotes 2 years ago

A user sharing their progress after using Fin, Minoxidil, keto diet, and microneedling for two months to attempt to regrow hair on bald temples. Other users replied with advice and support.

community Take A Vitamin D Blood Test!!!

Pepper7489 in Treatment 48 upvotes 2 years ago

Low Vitamin D can cause hair shedding, and taking 5000 IU of Vitamin D daily reduced shedding significantly. Vitamin D deficiency is common and correcting it can benefit overall health.

community Dutasteride and Finasteride Charts Website - You have more Dutasteride in your blood than you think

IndependentUsual7131 in Finasteride/Dutasteride 19 upvotes 8 months ago

Charts show how long Finasteride and Dutasteride stay in the blood, explaining why 0.5 mg Finasteride is less effective than 1 mg. Dutasteride accumulates over time, leading to gradual results compared to the immediate effects of Finasteride.

community Nuclear Stack Ineffective: Oral DUT/FIN/MIN/RU - NAFLD?

Nofacescott in Finasteride/Dutasteride 1 upvotes 7 months ago

The user experienced severe hair shedding despite using oral finasteride, minoxidil, dutasteride, and RU58841, and was diagnosed with Non-Alcoholic Fatty Liver Disease (NAFLD). They are considering switching to topical treatments due to the ineffectiveness of their current regimen.

community Minoxidil alternative with a week long half-life? Why isn’t it possible?

peterstiglitz in Satire 2 years ago

This conversation discussed the potential for a hair loss treatment alternative to minoxidil, with many users debating the economic and health implications of such an option. Some suggested that finasteride could be used as an alternative, while others argued that this would ultimately not benefit pharmaceutical companies due to their reliance on planned obsolescence.

community switched from topical to oral minoxidil (topical mixed with water) 3 months ago and aside from being much easier i’ve also had much more density overall. My results aren’t even finished yet!

Frosty_Wedding8706 in Progress Pictures 2 years ago

This user discussed using oral minoxidil as a hair loss treatment, and was cautioned against mixing topical minoxidil with water and drinking it due to potential side effects and risks. Other users shared their concerns about the dangers of self-prescribing medications without consulting a doctor.

community blood DHT levels shot up after doubling dutasteride dosage

BlitzKrister in Finasteride/Dutasteride 20 upvotes 8 months ago

A user increased their dutasteride dosage from 0.5mg to 1mg daily, resulting in a rise in DHT levels from 148 pg/mL to 281 pg/mL, and is considering switching back to finasteride due to continued hair loss. Replies suggest retesting and emphasize the importance of bloodwork before starting treatments.

community Progress: 0.5mg finasteride + 2.5 mg oral minoxidil

ss161616 in Progress Pictures 431 upvotes 2 years ago

This user uses a combination of finasteride and oral minoxidil to treat hair loss, and reports that the treatment has had an impact on his growth without any major side effects. He also shares advice on how to obtain the necessary medications in certain countries.

community pictures before I started pyrilutamide (repost)

Automatic-Law-3612 in Progress Pictures 124 upvotes 1 year ago

Automatic-Law-3612's progress with hair loss treatments, including topical finasteride, topical dutasteride, minoxidil and pyrilutamide. They have been using these products for two weeks and noticed baby hairs in their temples getting longer.

community Has anyone tried PRP therapy? Experience?

TheBrownKnight2 in Technology 4 upvotes 1 year ago

User visited derma doctor, suggested finasteride, minoxidil, multivitamins, and PRP therapy. Another user advised against PRP due to cost and ineffectiveness.

community Impressed by the progress but think it’s time to go for the transplant?

maurauth in Progress Pictures 288 upvotes 1 year ago

The user started taking 2.5mg minoxidil tablets daily and reduced their finasteride dose to 0.5mg due to side effects. They are considering a hair transplant but are unsure if they should proceed now or wait after seeing the effects of the reduced finasteride dosage.