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      community Testosterone and hair loss seeming irrelevance

      in Research/Science  80 upvotes   1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

      community Been on Min and Fin for Years and I am Devastated.

      in Treatment  64 upvotes   2 years ago
      Guyman567 has been using oral finasteride and topical minoxidil for years but continues to experience hair loss and thinning, which has affected his confidence. He has tried various treatments including topical finasteride, microneedling, and vitamins, and is considering a hair transplant but is concerned about ongoing hair loss.

      community #BIG4 plus vitamins and biotin/ 6 Months results/ 26 years old/ Extreme MPB

      in Progress Pictures  236 upvotes   2 years ago
      A 26-year-old with extreme male pattern baldness saw hair regrowth after 6 months using Minoxidil, Finasteride, microneedling, Nizoral, a vitamin complex, biotin, and a shampoo with baicapil. Continuation of treatment is necessary to maintain results; stopping may lead to hair loss, making a hair transplant a potential future option.

      community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

      in Progress Pictures  224 upvotes   4 months ago
      A user shared their 11-year experience with spironolactone and nearly 5 years with finasteride for hair loss, recently adding oral minoxidil and stopping birth control. Various treatments were discussed, including organic options, checking for underlying health issues, considering dutasteride, and the potential role of progesterone in hair loss.

      community Is this broscience? From More Plates, More Dates

      in Research/Science  21 upvotes   5 months ago
      The conversation discusses whether finasteride's reduction of DHT and increase in scalp testosterone contribute to hair follicle miniaturization. Some participants argue testosterone does not cause miniaturization, while others suggest that even with reduced DHT, other androgens like testosterone may still contribute to hair loss.

      community Diagnosed with female pattern hair loss as a male with recent aggressive loss. Preemptively mourning the only part of myself I’ve ever come close to loving. Lost all motivation to do anything with my life.

      in Progress Pictures  271 upvotes   11 months ago
      The conclusion of the conversation is that the user should consider using treatments such as finasteride, minoxidil, and RU58841 to potentially reverse their hair loss. Other suggestions include using hair loss concealers and maintaining a healthy diet.

      community PYRILUTAMIDE KX-826 experience

      in Research/Science  100 upvotes   2 years ago
      A user's experience with the hair loss treatment Pyrilutamide KX-826, which has resulted in some side effects and shedding. The conversation also includes advice for baseline pictures and trying treatments for at least 6 months.

      community It’s crazy how it’s 2018 and the only hair loss treatments we have feature undesirable side effects and/or aren’t even effective for many people.

       136 upvotes   6 years ago
      Hair loss treatments, including minoxidil, dermarolling, finasteride, dutasteride, hair transplants, hair systems, and shaving the head. The conversation covers various opinions on these treatments and mentions possible side effects as well as alternatives like wigs, vitamins, and lifestyle changes. The post expresses disappointment that there has been no major breakthrough in the field of hair loss treatments despite decades of research.

      community Hair Remedies that Don’t Work for Anybody Seeking Hair Regrowth

      in Treatment  7 upvotes   3 years ago
      Hair loss treatments discussed include minoxidil, finasteride, and RU58841. Salon products and supplements generally don't work for hair regrowth unless there's a severe nutritional deficiency, while hormonal treatments like estrogen and spironolactone can be effective.

      community Some of y’all need to hear this

      in Chat  353 upvotes   1 year ago
      Understanding that the importance of hair loss should not be overstated and encouraging self-love and confidence regardless of physical appearance. People discussed how they were feeling about their own hair loss and shared tips on treatments like Minoxidil, Finasteride and RU58841.

      community Don't give up! 9 months on Minoxidil

      in Progress Pictures  394 upvotes   3 months ago
      A trans man shared progress pictures showing significant hair regrowth after 9 months on oral Minoxidil and 1.5 years on finasteride. He encourages others to stick with their treatments despite initial setbacks.

      community Reflex Hyperandrogenicty: How I recovered from it

      in Treatment   10 months ago
      The user experienced severe hair shedding from RU58841 and recovered by stopping its use and starting treatments including Minoxidil, Rosemary Verbenone, Stemoxydine, Aminexil, copper peptide serum, and specific shampoos. They also consistently used oral Finasteride and plan to try Minoxidil 10%.

      community Hair loss and ethnicity - Caucasian men the most likely to experience hair loss

      in Chat  17 upvotes   1 year ago
      The conversation discusses how Caucasian men are more likely to experience hair loss due to genetic predisposition, with factors like the androgen receptor on the X chromosome playing a significant role. The user also expresses confusion about the evolutionary reasons for hair loss, especially in colder climates where it would seem beneficial to retain hair for warmth.

      community FCE 28260: A Forgotten 5α-Reductase Inhibition

        4 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Will my liver get destroyed long term on this stack ??

      in Chat  15 upvotes   6 months ago
      A user is considering a long-term hair loss treatment stack including Dutasteride, Finasteride, and oral Minoxidil, and is concerned about potential liver damage. Some responses suggest the stack is excessive, while others believe it's not harmful to the liver, but recommend regular blood work to monitor health.

      community Another clueless guy fearmongering and spreading misinformation

      in Chat  249 upvotes   6 months ago
      The conversation discusses hair loss treatments, with some users advocating for finasteride and minoxidil, while others express concerns about potential side effects of finasteride. A social media influencer is criticized for promoting scalp massages and minoxidil over finasteride, which some believe is misinformation.

      community 35m 1.5 months on oral fin/min is it too good to be true?

      in Progress Pictures  163 upvotes   10 months ago
      A 35-year-old man, balding since 18, has seen growth of small, almost white hairs all over his scalp after 1.5 months on oral finasteride and minoxidil. Users suggest sticking with the treatment for a year, adding microneedling, and potentially trying RU58841 or dutasteride.

      community Why creatine and gym cause MPD

      in Finasteride/Dutasteride   1 year ago
      Gym and creatine can cause hair loss by increasing testosterone and androgenic activity. DHT blockers may help some, while others need androgen suppression with topical AA like RU or Pyri.

      community Blood DHT Levels – before and after creatine

      in Research/Science  41 upvotes   1 year ago
      The impact of creatine on DHT levels, and whether it could cause accelerated male pattern baldness (MPB). The user taking a 5 alpha reductase inhibitor found that their DHT levels actually reduced despite taking creatine for nine weeks. Replies suggested looking into testosterone levels as well and debating the safety of creatine use in relation to MPB.

      community I feel like people here shrug off nutritional issues too quickly. Particularly for Retrograde Alopecia.

      in Chat  8 upvotes   1 year ago
      The user believes Retrograde Alopecia may be linked to vitamin imbalances, specifically from taking too much Vitamin E, A, Zinc, and Selenium, and suggests it could be a middle ground between Androgenic Alopecia and Telogen Effluvium. Treatments for hair loss mentioned include Androgen inhibitors and improving lifestyle factors like nutrition and sleep, with topical melatonin also recommended for Retrograde Alopecia.

      community Fin/Min/VitD 3 month progress pics

       119 upvotes   5 years ago
      A user shared their positive 3-month experience using finasteride, minoxidil, and vitamin D to treat hair loss, noting significant regrowth and minimal shedding. They also discussed potential side effects and the low likelihood of experiencing them, while being open to answering further questions.

      community blueprint is working so well it seems

      in Chat  540 upvotes   3 weeks ago
      The conversation discusses a person successfully using a combination of Minoxidil, finasteride, and other treatments for hair loss, resulting in significantly improved hair. Despite some criticism, many admire his dedication to health and anti-aging research.

      community Why does it seem everyone favors finasteride over dutasteride?

      in Female  62 upvotes   3 months ago
      The conversation discusses preferences for hair loss treatments, specifically finasteride over dutasteride. Users share personal experiences, cost considerations, FDA approval status, and potential side effects, with some switching between treatments to find what works best for them.