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      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  65 upvotes 1 year ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community 40 years old. 5 months progress. New hair coming in daily.

      in Progress Pictures  123 upvotes 1 year ago
      The user "mynameisbogus" shared their hair loss progress using various treatments including Dutasteride, RU, oral minoxidil, topical treatments, microneedling, dermastamping, rosemary oil, and scalp massaging. Other users commented on the extensive regimen and expressed their opinions.

      community how important is microneedling?

      in Finasteride/Dutasteride  17 upvotes 1 year ago
      User takes topical finasteride/minoxidil with little results, asks if microneedling helps for temple regions and if 0.5mm is enough. Replies suggest microneedling is effective and 0.5mm works, sharing personal regimens.

      community Hair Loss Due To Chlorine and Hard Metals In Water?

      in Research/Science  1 upvotes 1 month ago
      Hair loss possibly caused by chlorine and heavy metals in water was addressed by using a shower filter, ketoconazole shampoo, and PRP sessions, which stopped the hair loss but did not lead to regrowth. Other users suggested similar experiences and solutions, emphasizing the importance of a good water filter and patience for potential regrowth.

      community MY 6 MONTH TRANSFORMATION PROGRESS

      in Progress Pictures  210 upvotes 4 months ago
      A 23-year-old male shared his 6-month hair transformation using Dutasteride, oral Minoxidil, ketoconazole shampoo, vitamin D, gym, cardio, and dermastamping. He reported significant hair maintenance and no side effects.

      community Is ketoconazole very effective?

      in Ketoconazole  10 upvotes 5 months ago
      A user is considering using ketoconazole shampoo for hair loss and is seeking feedback on its effectiveness. They are asking for before and after photos or success stories.

      community Less messy way of applying minoxidil

      in Chat  25 upvotes 7 months ago
      The conversation suggests using a dropper to apply minoxidil to the scalp without force for a less messy application compared to sprays or other methods.

      community I was a non-responder to Minoxidil before my esophagus surgery

      in Research/Science  38 upvotes 10 months ago
      The user experienced improved hair density after switching from 5mg to 2.5mg oral Minoxidil post-esophagus surgery, suggesting a possible link between gut health and hair growth. They theorize that long-term medication may have blocked nutrient intake, affecting hair regrowth.

      community 5 weeks of Minoxidil. Early results of regrowth? 😬

      in Is this regrowth?  133 upvotes 1 year ago
      The user is seeking feedback on their hair regrowth progress after using Minoxidil for 5 weeks, along with other treatments. Some users share their experiences, mentioning that Minoxidil may not provide a permanent solution and that results vary. It is advised to take before pictures for better assessment.

      community 4 months on 2.5 mg OM, no improvement

      in Minoxidil  6 upvotes 1 year ago
      After 4 months on oral minoxidil with no significant hair regrowth, a user is frustrated and considering alternative treatments since they can't take finasteride due to side effects. Suggestions include natural DHT blockers, lifestyle changes, and other hair care tips.

      community Hair loss treatment rabbit hole [OC]

      in Satire  317 upvotes 2 years ago
      Hair loss treatments, ranging from topical minoxidil and finasteride to taking hormones such as estradiol or nandrolone, as well as a controversial suggestion of an orchiectomy. A hair system is also mentioned as an alternative solution.

      community The 'DHT itch' is real - notes from a casual bodybuilder

      in Chat  115 upvotes 2 months ago
      The "DHT itch" is real and likely due to inflammation at the hair follicle, exacerbated by increased testosterone or androgens. Treatments mentioned include dutasteride, minoxidil, finasteride, and various topical solutions.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 3 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Why balding gets worse in every generation?

      in Chat  81 upvotes 5 months ago
      Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.

      community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

      in Progress Pictures  224 upvotes 7 months ago
      A user shared their 11-year experience with spironolactone and nearly 5 years with finasteride for hair loss, recently adding oral minoxidil and stopping birth control. Various treatments were discussed, including organic options, checking for underlying health issues, considering dutasteride, and the potential role of progesterone in hair loss.

      community How uninformed the general public is about hair loss

      in Chat  313 upvotes 9 months ago
      The conversation highlights the general public's lack of knowledge about hair loss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.

      community Finasteride won’t make all your problems go away

      in Finasteride/Dutasteride  323 upvotes 11 months ago
      A user shared that while finasteride improved their hair, it didn't solve all their insecurities, suggesting that self-acceptance is key. Others in the conversation expressed varying opinions, with some feeling that finasteride significantly boosted their confidence and quality of life, while others acknowledged it as a solution to hair loss but not a cure-all for other personal issues.

      community How much does diet affect hair loss?

      in Chat  45 upvotes 1 year ago
      The conversation suggests that changing diet and lifestyle has little to no effect on male pattern baldness (MPB), which is largely determined by genetics. Some individuals noted personal improvements in hair condition with healthier diets, but the consensus is that diet alone cannot prevent or reverse MPB.

      community I’m just Going to let Nature take its Course

      in Chat  213 upvotes 1 year ago
      The post and conversation are about a 23-year-old deciding to stop using finasteride for hair loss due to potential erectile dysfunction risks, sparking a debate about the benefits and side effects of hair loss treatments.