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      community KX-826 Phase 3 Failed. Sorry guys...

      in Research/Science  52 upvotes 11 months ago
      The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.

      community C’est terrible - at my wits end

      in Female  445 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community Bloodwork reports just came in

      in Update  23 upvotes 1 year ago
      A 21-year-old male suffering from male pattern baldness is using topical finasteride and minoxidil, and oral minoxidil. His bloodwork shows normal DHT levels and slightly high testosterone, leading to discussions about the role of DHT sensitivity in hair loss, the potential impact of finasteride on his DHT levels, and the suggestion to proceed with oral finasteride due to his high testosterone.

      community 48 days of Fin, Min, and Dermaroller

      in Progress Pictures  1746 upvotes 1 year ago
      The user has been using finasteride for hair loss for 2-3 years, and added 5% topical minoxidil and daily 1.5mm dermarolling to their routine 50 days ago, which resulted in significant hair growth. The user recommends dermarolling along with minoxidil and finasteride for better results.

      community Minoxidil seems logistically impossible and impractical to use

      in Minoxidil  136 upvotes 1 year ago
      The post discusses concerns about the practicality of using Minoxidil foam for hair loss, including the frequency of application, preparation, coverage area, and drying time. Responses suggest that missing a dose isn't detrimental, it can be applied once a day, it works on all hair areas, and it doesn't need to be perfectly dry before application.

      community Are there ever going to be any oral DHT blocking treatments in the future?

      in Product  6 upvotes 1 year ago
      The discussion revolves around the need for future oral DHT blockers for hair loss treatment that don't have the side effects of current options like Finasteride and Dutasteride. One user suggests that the future of hair loss treatment will likely be topical anti-androgens, as they can target hair follicles without affecting the entire system.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  65 upvotes 1 year ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community I just made my own PRP - DIY PRP

      in Research/Science  549 upvotes 1 year ago
      The post and conversation are about a user who made their own Platelet-Rich Plasma (PRP) for hair loss treatment at home, using their own blood and a centrifuge. The responses vary, with some users supporting the DIY approach to save money, others expressing concern about the safety and effectiveness of the method, and a few joking about the lengths people will go to combat hair loss.

      community 2 years. More hair. Dut, Oral Min, RU, Niz

      in Progress Pictures  182 upvotes 1 year ago
      A user's two-year hair regrowth journey using 0.5 mg Dutasteride, 5mg oral Minoxidil, 0.75ml of 8% RU58841, and Nizoral shampoo a few times a week. Other users suggest adding microneedling and topical Minoxidil for better results.

      community hims finasteride spray diluted to O.1% fin

      in Progress Pictures  252 upvotes 1 year ago
      The user shared their positive experience with a hair loss treatment regimen, which includes a diluted version of Hims finasteride spray, Kirkland 5% minoxidil, and weekly dermarolling. The user also mentioned taking hair multivitamins and plans to continue updating on their progress.

      community 3 months on Hims Topical Spray

      in Progress Pictures  429 upvotes 1 year ago
      The user has been using Hims finasteride and minoxidil spray, nizoral shampoo twice a week, and a daily biotin gummy for 90 days to treat hair loss. The user and others discuss the cost, dosage, and effectiveness of the treatment, with some suggesting cutting hair short for better results.

      community Sublingual Minoxidil - Cure to Hairloss?

      in Minoxidil  583 upvotes 1 year ago
      The conversation discusses the potential benefits of sublingual minoxidil for hair loss treatment. It suggests that sublingual minoxidil, which bypasses the liver, may have fewer side effects, greater bioavailability, and could be more effective than oral minoxidil.

      community Caffeine & Alopecia: What the Science Seems to Say

      in Research/Science  17 upvotes 1 year ago
      The conversation discusses the potential benefits of topical caffeine for Androgenetic Alopecia (APA) and female pattern hair loss. While some studies suggest positive results, there's no reliable scientific evidence to strongly recommend caffeine compounds for hair regrowth.

      community New Treatments, and a Huge Group Buy with Lots of Research

      in Research/Science  109 upvotes 1 year ago
      A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

      community 6 month update of 1 mg fin only

      in Progress Pictures  30 upvotes 1 year ago
      A user shared a 6-month hair loss progress update using 1 mg finasteride, plans to start minoxidil and RU58841 due to severe shedding, and seeks advice. Others suggest maintaining treatment, switching to different medications, and considering more aggressive treatments due to strong genetic predisposition to baldness.

      community 5 month results on natural protocol, i made a post after 3 mont of treatment wich you can find in my profile. I used different massages(detumescence therapy, wooden brush, tom hagerty exercises)vitamins(d3,fish oil, biotin,msm, magnesium) drank green tea and ate pumpkin seeds( reduces dht)

      in Is this regrowth?  151 upvotes 1 year ago
      The user "Zealousideal-Pack340" shared their 5-month results on a natural hair loss treatment protocol, which included massages, vitamins, green tea, and pumpkin seeds. Some users suggested using medications like finasteride and minoxidil for better results, while others criticized the effectiveness of natural remedies. Overall, there was no clear consensus on the progress of the user's hair regrowth.

      community Vitamin Deficiency: “Severely” Low on Vitamin D

      in Update  15 upvotes 1 year ago
      A user experiencing significant hair loss found they had a severe vitamin D deficiency and was prescribed 50,000IU vitamin D pills, likely to be taken weekly. They are questioning if the deficiency could be the cause of their hair loss and if correcting it could stop the shedding and improve hair recovery.

      community Anybody use both oral & topical minoxidil?

      in Minoxidil  339 upvotes 1 year ago
      The user "macroburstmedia" is asking if adding topical minoxidil to their current treatment of oral minoxidil and finasteride can improve hair growth. Some users have shared their experiences with using both oral and topical minoxidil, while others suggest increasing the oral minoxidil dose instead.

      community 11 month progress on a cocktail regiment

      in Progress Pictures  435 upvotes 1 year ago
      The user "Dismal_Library_2264" shared their 11-month progress on a hair loss treatment regimen. They used dutasteride, topical minoxidil, dermarolling, a hair serum, and specific shampoos. They experienced some side effects but were overall satisfied with the results.

      community Losing hair as teenager Dont know what to do

      in Chat  3 upvotes 1 year ago
      A teenager started balding at 13 and has been using minoxidil for 2 years, but the hair loss is returning. They are seeking advice on additional treatments. Another user suggests finasteride or shaving the head, and emphasizes the importance of not letting hair loss affect self-esteem and relationships.

      community Tretinoin can make it worse!!!

      in Chat  7 upvotes 1 year ago
      Tretinoin may enhance minoxidil's effectiveness for those not responding to minoxidil alone, but it could reduce efficacy for some who are already responding to minoxidil. Tretinoin requires careful use, including skin moisturizing and sun protection due to increased sensitivity.

      community NW5 at 19. How many grafts do I need?

      in Transplants  140 upvotes 1 year ago
      A 19-year-old with rapid hair loss since 16 is considering a hair transplant but refuses to take finasteride or any 5α-Reductase inhibitors. They are currently using minoxidil, tretinoin, and microneedling with a Derminator 2, and only want hair until age 27.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  81 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.