New product Tomorrowlabs HSF targets hair loss through HIF pathway indirectly by removing scalp iron. Minoxidil and Stemoxydine also relate to HIF pathway.
User got a hair transplant and it improved their life. Transplanted hair lasts, but medication like finasteride is needed to maintain non-transplanted hair.
User experienced hair thickening with pyri but also side effects like reduced sex drive. Stopping pyri and returning to CB restored sex drive, suggesting pyri may go systemic or be incorrectly formulated.
User frustrated with lack of improvement after 1 year and 3 months using Minoxidil, Finasteride, and microneedling for hair loss. Replies suggest considering oral Minoxidil, switching to Dutasteride, and potential hair transplant.
A user's 7-month progress using 1 mg finasteride and topical minoxidil, with no side effects from the finasteride, achieving baby hairs on the hairline and other positive results. Other users have discussed different treatments such as microneedling and supplements, providing advice and encouragement to the poster.
A Phase II clinical trial for TDM-105795 has started recruiting in the US, and it might be a promising treatment for hair loss. Many hair loss drugs, including this one, originate from China.
A user's experience of gaining weight while taking Dutasteride, and suggestions on how to continue using it without the negative side effects, such as exercising and tracking calories or switching to Finasteride.
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CumsOnYourFeet69 has been discussing a new treatment called CosmeRNA which claims to target the root cause of male pattern baldness, and is considering using it in conjunction with Minoxidil instead of Finasteride due to possible side effects. Replies have highlighted that the efficacy of this treatment is still unknown, but it could be used as an effective maintenance option if successful.
Phase II for TDM-105795 for Androgenic Alopecia is set to begin in April 2023. The study aims to evaluate the efficacy and safety of TDM-105795 in male subjects.
A user's success with treating their hair loss using daily finasteride and minoxidil, and his experience of restored confidence. Replies to the post include discussion about the optimal dose for minoxidil, as well as warnings regarding the high dose taken by the original poster.
Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.
_the_orange_box_'s experience using oral minoxidil, with discussion about finasteride and the potential side effects of both treatments. Other users shared their own experiences related to hair loss treatments.
This user has had positive results from taking a 1 mg dose of finasteride and increasing their daily dosage of minoxidil from 2.5 to 5 mg over the course of 9 months.
A user's 2.5 months of finasteride, oral minoxidil, and dermarolling treatments for hair loss, with various users giving their opinion on the progress made.
Creating a carrier solution for topical hair loss treatments using ethanol, propylene glycol or glycerin, and instructions on creating topical finasteride. Different recipes are provided with varying ratios of alcohol to humectant.
Pyrilutamide is considered to work for hair loss but less effectively than expected, similar to RU58841, and may cause side effects like chest tightness and sexual issues. It's unclear if it's suitable for diffuse thinners, and one user cannot use minoxidil or finasteride due to side effects and personal circumstances.
A user's 18-month progress on their hair loss treatment regimen, which includes 5mg oral minoxidil, 1.5mm microneedling with a pen once weekly, and 0.5mg/day dutasteride; other users noted the positive effects of finasteride and dutasteride in reducing DHT levels.
The post discusses using finasteride, minoxidil, ketoconazole, and a dermaroller for hair loss, along with spearmint capsules, pueraria mirifica, saw palmetto, biotin, and vitamins. The user is also considering microdosing finasteride with trans treatment and mentions the potential of herbal enemas and hair systems.
The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.
A user had a bad reaction to Finasteride, experiencing anxiety and fatigue, and is seeking alternative hair loss treatments since they can't use Finasteride or Minoxidil. Suggestions include trying low doses of Finasteride, making a topical version, or using other treatments like Alfatradiol, but the user is hesitant to use Finasteride again and is considering a hair transplant.
A user's results after using finasteride (1.25mg/day) for one year, which included improvements to their hair and skin as well as some side effects such as decreased libido and watery semen. They also mentioned they stopped taking creatine around the same time.
A 7-month update from Markoj44 regarding their hair transplant results, which includes the use of topical finasteride and minoxidil in combination with Viviscal, biotin, Nizoral shampoo, and donor area photos. People responded positively to the post.
Treating the itch associated with male pattern baldness, which is believed to be caused by DHT. Potential treatments discussed include salt water, finasteride, ketoconazole, and RU58841.
A human trial of verteporfin, a potential treatment for hair loss, with some users noting potential improvements in scarring and overall healing compared to control areas.
The conversation discusses which vitamins to take alongside 0.5mg finasteride for hair loss, with suggestions including a multivitamin, iron, zinc, B12, vitamin D, Nutrafol, collagen, vitamin C, saw palmetto, and magnesium. Nutrafol is noted for its benefits but also criticized for containing too much biotin.
User switched from Fin to Dut for better hair loss results, using 0.5mg Dut and 1ml Min daily. Some discuss potential side effects and benefits of Dut compared to Fin.
User asks about topical spironolactone experience. Two studies show it as promising anti-androgen treatment, with 5% cream available on Minoxidilmax website.
A user's 5 month progress with their hair loss treatment which includes topical finasteride and minoxidil, microneedling once every 10 days, and keto shampoo twice a week. Other users shared their own experiences and advice on treatments.
User taking 1mg finasteride daily for 2 years, wants to block more scalp DHT. Seeks reference for additional topical DHT blockers like alfatradiol and fluridil.