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      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 4 months ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.
      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 5 months ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

      community Oxytocin, empathy, hair, and cinnamon

      in General  138 upvotes 5 months ago
      Low oxytocin levels in hair are linked to reduced empathy and may affect hair growth. Cinnamic acid can promote hair growth by activating oxytocin receptors.
      Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      in Treatments  451 upvotes 5 months ago
      Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

      community Getting Ed from 1mg of fin not sure what to do

      in Finasteride  190 upvotes 5 months ago
      The user experienced erectile dysfunction from 1mg finasteride and sought advice on whether to continue, reduce dosage, or switch treatments. Suggestions included switching to topical finasteride, adding minoxidil, or trying dutasteride.
      Is this a male pattern baldness or diffuse baldness?

      community Is this a male pattern baldness or diffuse baldness?

      in General  144 upvotes 5 months ago
      A 23-year-old male experienced sudden hair loss over six months, losing about 30% of his hair. Treatments include 10% minoxidil, a hair spray, and a vitamin pill; opinions on the cause vary between normal hair loss due to deficiencies and male pattern baldness.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  822 upvotes 5 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community How to know if shedding is from tren or minoxidil?

      in Minoxidil  5 upvotes 9 months ago
      The user started using trenbolone and minoxidil simultaneously and experienced increased hair shedding, unsure which is causing it. Replies suggest both drugs could cause hair loss, with one advising to stop trenbolone to protect hair and another indicating minoxidil is unlikely the cause due to the timing.
      September to December

      community September to December

      in Journals / Progress Pictures  86 upvotes 1 month ago
      The user shared progress pictures showing hair improvement from September to December using topical finasteride 0.3% and minoxidil 6%. The treatment appears to be effective for hair loss.
      Guys I need advice more hairs in the drain

      community Guys I need advice more hairs in the drain

      in Journals / Progress Pictures  242 upvotes 2 months ago
      The user is experiencing significant hair shedding after starting dutasteride, which is considered a normal part of the treatment process. Despite the shedding, the user notes some improvement in hairline appearance and is seeking advice and reassurance.

      community Dutasteride RAISES LIBIDO!

      in Treatments  222 upvotes 7 months ago
      Dutasteride can significantly increase libido, more so than finasteride. Users reported higher libido when switching from finasteride to dutasteride.

      community HUGE COMEBACK! 10 Month Progression as a 19yo

      in Progress Pictures  30 upvotes 11 months ago
      A 19-year-old has seen hair regrowth after 10 months using finasteride and recently added minoxidil and tretinoin. They experienced no side effects from the treatments and are optimistic about further improvement.

      community Long term minoxidil as a permanent solution

      in Minoxidil  26 upvotes 3 years ago
      A user is considering using minoxidil for hair loss and asks for advice on application and long-term effectiveness. Responses suggest minoxidil can be effective but may lose efficiency over time, and combining it with other treatments like finasteride might be more beneficial.

      community Topical aldactone for men’s hair and muscle effects

      in Treatments  18 upvotes 4 weeks ago
      Topical aldactone is discussed for its effects on men's hair and muscles. The conversation explores its potential benefits and side effects compared to other treatments like Minoxidil, finasteride, and RU58841.
      2 months into Minoxidil, poor sleep however, is it over for me?

      community 2 months into Minoxidil, poor sleep however, is it over for me?

      in Minoxidil  54 upvotes 1 month ago
      A 21-year-old university student started using Minoxidil and derma stamping for hair loss over two months ago. Despite poor sleep due to exams, the student is hopeful about improving their sleep schedule during the holidays and notes their hairline remains straight.

      community Would RU58841 work on a test cycle?

      in Technology  1 upvotes 3 months ago
      OP experienced side effects from finasteride and is considering using RU58841 to prevent hair loss during a testosterone cycle. They have also used minoxidil, Nizoral, alfatradiol, and fluridil successfully.

      community Chest discomfort on finasteride?

      in Finasteride  72 upvotes 4 months ago
      A user experienced chest discomfort after taking finasteride for hair loss and is concerned about whether it is a side effect or an allergy. They are advised to consult a doctor and consider other hair loss treatments if necessary.

      community Warning: Your Rogaine Foam Might Not Contain Minoxidil

      in Minoxidil  373 upvotes 6 months ago
      A user experienced significant hair loss after using Rogaine foam purchased from Amazon, which failed a bleach test for Minoxidil. They discovered that even legitimate Rogaine products might be faulty and advised buying from reputable sources.