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      community Comparing the effect of T suppression and DHT suppression

      in Transgender  61 upvotes 4 months ago
      The conversation discusses the use of 5-alpha-reductase inhibitors like finasteride and dutasteride for hair loss in transgender women, particularly in relation to testosterone suppression. The original poster has been using dutasteride and is considering stopping it due to undetectable testosterone levels.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Using both oral fin/min and topical fin/min?

      in Treatments  62 upvotes 5 months ago
      The conversation discusses using both oral and topical forms of finasteride and minoxidil for hair loss. Concerns about potential overkill and side effects are raised, but no side effects are reported from using oral finasteride and topical minoxidil.

      community Cmon Pyrilutamide and CosmeRNA 😭

      in Chat  36 upvotes 1 year ago
      Users discuss waiting for new hair loss treatments and share struggles with side effects from current options like Minoxidil and Finasteride. They express hope for Pyrilutamide and CosmeRNA to provide better solutions.

      community Minoxidil + tretinoin usage frequency

      in Minoxidil  1 upvotes 3 months ago
      A user is seeking advice on how often to use a minoxidil solution with 0.025% tretinoin, considering using it every other evening instead of regular minoxidil twice a day. They are asking for experiences and opinions on this usage frequency.

      community Where are GT20029 phase II results?

      in Research/Science  3 upvotes 11 months ago
      The conversation is about the anticipation of results for a hair loss treatment study, specifically for GT20029, with expectations for the results to be released in the first quarter of 2024. No specific treatments were discussed.

      community Progress pics April 30 to Aug 9

      in Progress Pictures  300 upvotes 1 year ago
      The user "mspamnamem" shares their progress with a hair loss treatment stack consisting of finasteride, minoxidil, biotin, and microneedling. They express satisfaction with their progress and hope for continued improvement. Other users in the conversation provide encouragement and share their own experiences.

      community Log #1 - My .25mg EOD Finasteride Journey

      in Finasteride/Dutasteride  6 upvotes 4 months ago
      A user started taking 0.25mg of finasteride every other day to prevent hair loss and documented their experience. Initially, they felt anxious and had headaches, but by the second week, they felt normal with no side effects or changes in hair.

      community Buzzed my hair today. Raised my confidence a lot.

      in Shaved/buzzed  428 upvotes 2 years ago
      A user who buzzed their hair, raising their confidence. Other users suggested trying finasteride to thicken the existing hair or using hair systems as an alternative. Additionally, toppik was suggested as a way to fill in thinning areas.

      community Nuclear stack: 2.5mg dutasteride vs 0.5mg dutasteride + topical finasteride/dutasteride/spironolactone for male pattern baldness

      in Research/Science  4 upvotes 1 month ago
      The conversation discusses using 2.5mg dutasteride, 0.5mg dutasteride with topical treatments, and other combinations like oral minoxidil, RU58841, and microneedling for male pattern baldness. Users share experiences and suggest various treatment regimens, emphasizing the effectiveness of dutasteride and minoxidil.

      community 1 year progress - fin only 1.25 daily

      in Progress Pictures  146 upvotes 6 months ago
      The conversation is about a user's one-year hair regrowth progress using 1.25mg of finasteride daily. Users are asking about the timeline of visible progress, the user's age, and whether they experienced shedding.

      community fin-min-keto-derma did not work for me. 24 yo

      in Update  16 upvotes 3 months ago
      A 24-year-old tried minoxidil, finasteride, keto shampoo, and derma-rolling for hair loss but saw no improvement and is now at Norwood 5. They feel there's nothing more they can do and are considering going bald despite not liking the look.

      community 5mg Oral Minoxidil - No Effects

      in Minoxidil  6 upvotes 4 months ago
      A user reported no effects after 2 months of taking 5mg oral minoxidil, with no shedding or regrowth. They are seeking advice on whether this is normal and if they should be discouraged.

      community Verteporfin and Microneedling

      in Treatments 5 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community [Serious] Experience with grey-market KX-826 (Pyrilutamide)

      in Research/Science  2 upvotes 1 year ago
      The user experienced reduced hair loss using grey-market KX-826 alongside Minoxidil foam, achieving better results with Minoxidil liquid but restricted to foam due to an allergy. Initial side effects included shortness of breath, racing heart, and dizziness, which subsided after the first week.

      community How much does diet affect hair loss?

      in Chat  45 upvotes 1 year ago
      The conversation suggests that changing diet and lifestyle has little to no effect on male pattern baldness (MPB), which is largely determined by genetics. Some individuals noted personal improvements in hair condition with healthier diets, but the consensus is that diet alone cannot prevent or reverse MPB.