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    GlossaryEstradiol (17beta-estradiol)

    potent estrogen hormone primarily produced in the ovaries

    Estradiol, also known as 17β-Estradiol or E2, is a potent estrogen hormone primarily produced in the ovaries. It plays a crucial role in regulating the menstrual cycle, reproductive system, and secondary sexual characteristics in females. Additionally, estradiol has significant effects on various tissues, including bone, skin, and hair, influencing growth and maintenance.

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      community Creatine's effect on Hair Loss and DHT

      in Research/Science  102 upvotes 9 months ago
      A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

      community 2 months on minoxidil 5% GOOD RESULTS?

      in Progress Pictures 2 years ago
      Asteride into your routine In this conversation, the user Icy-Indication267 was asking when they should start finasteride to treat their hair loss, which had responded well to minoxidil after two months. Other users shared advice on incorporating micro-needling and topical finasteride into their routine for optimal results.

      community Why am I so scared to start fin?

      in Finasteride/Dutasteride  15 upvotes 2 years ago
      User is scared to start finasteride for hair loss due to potential side effects and personal concerns. Another user suggests trying a low dose for 6 months and avoiding online groups to reduce anxiety.

      community 1 year Progress: Fin + Oral Min 5mg

      in Progress Pictures  407 upvotes 2 years ago
      A user's experience with finasteride and oral minoxidil for treating hair loss, which resulted in great regrowth and improved mental state. Other users asked questions about their own experiences with the treatments.

      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 2 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.