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      community The Perfect Stack: The Best Dosage of Hair Loss Medications

      in Chat  19 upvotes 5 months ago
      The conversation discusses hair loss treatments with varying dosages of finasteride, oral minoxidil, and microneedling based on the level of hair loss aggressiveness. Specific regimens include 1.25MG finasteride 3-5 times per week, 2.5MG oral minoxidil daily, 0.5-1.5MM microneedling weekly, and 0.5MG dutasteride 1-2 times per week for more aggressive cases.

      community M32, almost 3 moths, fin oral 1,25g/daily + min 2xday + keto 2% shapoo 1/week microneedling once a week

      in Progress Pictures  31 upvotes 10 months ago
      A 32-year-old man has been treating his hair loss with daily oral finasteride (1.25g), twice-daily topical minoxidil, weekly ketoconazole 2% shampoo, and weekly microneedling for almost three months, with no side effects from finasteride. He started with a Hamilton Norwood scale rating of 5 and has seen improvement without experiencing pain by using a 0.8mm needle length for microneedling.

      community Finasteride affects both 5a reductase and 5b reductase

       7 upvotes 5 years ago
      Finasteride not only inactivates the 5a reductase enzyme but also affects the 5b reductase enzyme in a dose-dependent manner, which can impact sexual behavior and brain activity. The user experienced significant hair regrowth and side effects on 1mg of finasteride, which diminished after reducing the dose to 0.5mg, leading to no side effects and further hair improvement.

      community This is my progress so far, what we thinking?

      in Progress Pictures  109 upvotes 7 months ago
      The user has been using finasteride for 6.5 months, topical minoxidil for about 4 months, and occasionally microneedling to treat hair loss, and is asking if the progress shown is appropriate for that time. Commenters are congratulating the user on the visible improvement.

      community 18/M 5 month transformation with RU58841 and minoxidil

      in Progress Pictures  442 upvotes 3 years ago
      An 18-year-old shared a 5-month hair transformation using RU58841 and minoxidil, reporting no side effects and crediting most regrowth to minoxidil. Opinions on RU58841 are mixed, with some users and a YouTuber moving away from it due to side effects and lack of studies.

      community biochemistry bros, is this hair loss solution viable?

      in Finasteride/Dutasteride  2 upvotes 2 months ago
      The conversation discusses using a combination of finasteride, spironolactone, minoxidil, retinol, azelaic acid, and caffeine for hair loss treatment. The user inquires about the limitations of these drugs and whether tretinoin would be more effective than retinol.

      community 6 Months Min and 3 Months Fin Results

      in Progress Pictures  192 upvotes 2 months ago
      User shared progress pictures showing significant hair improvement after 6 months of Minoxidil and 3 months of Finasteride, along with dermastamping twice a week. Another user encouraged them to continue the good work.

      community Verteporfin and Microneedling

      in Treatments 3 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community thoughts on topical Saw Palmetto oil

      in Treatment  4 upvotes 3 months ago
      The user is considering topical Saw Palmetto or Pumpkin Seed Oil due to sensitivity to finasteride and cost issues. They also use dermastamping for Minoxidil absorption and seek advice on timing to avoid systemic absorption.

      community Why is it that low testosterone causes hair loss as well? How can I be balding?

      in Chat  158 upvotes 5 months ago
      The conversation discusses the confusion over low testosterone potentially causing hair loss, with users sharing personal experiences and knowledge about hair loss treatments like Finasteride. Some users suggest that hair follicle sensitivity to DHT, not testosterone levels, is the key factor in balding, and others discuss the side effects of hair loss medications.

      community It works. About a 1 year transformation.

      in Progress Pictures  613 upvotes 1 year ago
      A user's experience with hair loss treatments, specifically Minoxidil and finasteride, which they have used without side effects for a year. Other users shared their experiences and advice about potential side effects and supplements to help.

      community 2 years dutasteride + 1 year minox

      in Progress Pictures  41 upvotes 1 year ago
      A hair loss regimen that includes oral dutasteride and topical minoxidil, as well as occasional dermapen treatments; the user inquires about when they noticed most regrowth.

      community How are you guys using tretinoin on your scalp?

      in Treatment  6 upvotes 1 year ago
      People are discussing how to apply tretinoin to the scalp for hair loss treatment and managing scalp dryness. Specific treatments mentioned include tretinoin, minoxidil (Min), finasteride (Fin), and RU58841 (RU).

      community 6 months on oral minox with no result

      in Minoxidil  10 upvotes 1 year ago
      A user who had taken oral minoxidil for 6 months without seeing any results and the advice given in response, which included trying microneedling in combination with topical minoxidil, as well as seeking a dermatologist's opinion.

      community Does Minox give regrowth?

      in Minoxidil 4 years ago
      A user is using 1ml/day of Dualgen-15 (15% Minoxidil, caffeine, retinol, azaleic acid, Adenosine, biotin, niacin) on their temples and asks if Minoxidil alone can completely regrow their temples.

      community Finasteride + Cialis together long term?

      in Treatment  3 upvotes 1 month ago
      The user has been on 1mg finasteride for a year, experiencing low libido and moderate erectile issues. They are considering using Cialis daily with finasteride long term to address these side effects.

      community So... any chinese suppliers for real pyri?

      in Research/Science  6 upvotes 2 months ago
      The conversation discusses sourcing pyrilutamide from China for hair loss treatment, highlighting its potency compared to other AR antagonists like bicalutamide and RU58841. The user expresses interest in trying pyrilutamide despite mixed results in clinical trials.

      community Mixing Stemoxydine 5% with premixed solution of RU58841 5%

      in Research/Science  2 upvotes 5 months ago
      The user is using Dutasteride, Nizoral, and RU58841 for hair loss and is considering mixing RU58841 with Stemoxydine for better scalp coverage but is concerned about the potential degradation of RU58841 when mixed with a water-based solution. They are seeking advice on the feasibility of this mixture.

      community People call companies stupid for making very high concentration Topical Fin solutions but I think they overlook the fact that the actual absorption rate of finasteride varies greatly

      in Finasteride/Dutasteride  13 upvotes 6 months ago
      The conversation discusses how the absorption rate of topical finasteride varies and is not equivalent to its oral form, with only a small percentage reaching the scalp. It also mentions that minoxidil in high concentrations is used topically because only a small amount is absorbed.

      community Anyone have better luck with Dutasteride over Finasteride?

      in Finasteride/Dutasteride  8 upvotes 6 months ago
      The conversation is about someone who has tried various dosages of finasteride for hair loss without success and is considering switching to dutasteride, which reduces more DHT. They are asking if others have had issues with finasteride but found dutasteride to be more effective without problems.

      community Verteporfin trials in hair transplant patients begin

      in Transplants  44 upvotes 2 years ago
      A clinical trial for Verteporfin as a hair loss treatment, and the potential for greater progress in treatments for hair loss in the future. Common treatments such as Minoxidil, Finasteride and RU58841 were discussed.