Clascoterone
also Breezula, CB-03-01, Winlevi
- Phase 3 (Breezula) · topical · Cosmo Pharmaceuticals · trial NCT05910450 · sponsor targets early 2027 for US NDA filing (said Apr 2026)
Topical androgen-receptor blocker, approved as an acne cream
Clascoterone, sold under the brand name Winlevi, is an antiandrogen medication which is used topically in the treatment of acne. The medication is used as a cream by application to the skin, for instance the face and scalp. Clascoterone is an antiandrogen, or antagonist of the androgen receptor (AR), the biological target of androgens such as testosterone and dihydrotestosterone. It shows minimal systemic absorption when applied to skin.
Read “Clascoterone” on Wikipedia and its adverse effects · text from Wikipedia, CC BY-SA 4.0
Information, not medical advice. Talk to a licensed doctor or pharmacist before starting or changing a treatment.
Research 10
- Clascoterone: First Approval
- A Phase 1 Study to Investigate the Effects of Cortexolone 17α‐Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity
- Use of topical clascoterone for the treatment of hidradenitis suppurativa
- Real-World Experience of Clascoterone Cream 1% in Acne Management: Case Series and Canadian Experience
- Cortexolone 17α-Propionate (Clascoterone) is an Androgen Receptor Antagonist in Dermal Papilla Cells In Vitro
- Topical, light-based, and complementary interventions for acne: an overview of systematic reviews
- Androgens and acne: perspectives on clascoterone, the first topical androgen receptor antagonist
- Emerging pharmacotherapies for androgenetic alopecia
- Adverse Events Associated with Clascoterone: A Real-World Pharmacovigilance Study of the Food and Drug Administration Adverse Event Reporting System
- Living Probiotic Microneedles Coordinate Antiandrogen and Nitric Oxide Therapy for Androgenetic Alopecia
- Emerging pharmacotherapies for androgenetic alopecia
- Living Probiotic Microneedles Coordinate Antiandrogen and Nitric Oxide Therapy for Androgenetic Alopecia
- Adverse Events Associated with Clascoterone: A Real-World Pharmacovigilance Study of the Food and Drug Administration Adverse Event Reporting System
- Remarkable findings in male pattern baldness: sugar molecule 2dDR offers hope for hair regrowth
- Real-World Experience of Clascoterone Cream 1% in Acne Management: Case Series and Canadian Experience
- Topical, light-based, and complementary interventions for acne: an overview of systematic reviews
- Use of topical clascoterone for the treatment of hidradenitis suppurativa
- A Phase 1 Study to Investigate the Effects of Cortexolone 17α‐Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity
- Androgens and acne: perspectives on clascoterone, the first topical androgen receptor antagonist
- Clascoterone: First Approval
Posts 20
- Has anyone actually bought raw Clascoterone (CB-03-01) from Made-In-China? The prices are tempting, but am I crazy for considering this?
- Why are people so negative regarding Clascoterone (Breezula)?
- Why Breezula Won’t Work for Everyone.
- Women complaining of bad effects from Winlevi (Clascoterone 1%)
- CB-03-01 (Clascoterone): What Real-World Results Show for Hair Loss
- Wrap it up everyone. CB-03-01 is another failed treatment
- What the Breezula Phase III results mean & realistic timeline
- CB-03-01 / Breezula Personal Results
- Has anyone seen the data on this 539% boost breakthrough?
- Clascoterone - what we have right now
- The urge to buy Clascoterone 5% solution
- Breezula - who tried CB0301/Clascoterone from gray marked/pharmas ?
- This could be it!!! New treatment increase hair 500%
- FOL005 claims it's better than Finasteride and Minoxidil.
- Clascoterone 12 months phase 3 result out
- Breezula / Winlevi recent update
- Clarifying Science and Emotion regarding Clascoterone A.K.A. CB-03-01 / Breezula / Winlevi
- Whatever happened to Clascoterone? (breezula for hair) (sold as Winlevi for acne available since 2021)
- Clascoterone - Why are there so few posts if it’s already on the market?
- Chat is this real? Compound called clascoterone