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research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne

65 citations , February 2009 in “The journal of investigative dermatology/Journal of investigative dermatology”

This paper discusses the hypothesis that anti-acne agents may work by reducing FGFR2 signaling, and emphasizes FGFR2's potential role in acne pathogenesis, but it reports no new experimental findings.

research Traditional and Contemporary uses, Phytochemistry and Pharmacology of Psoralea corylifolia Linn.

January 2024 in “Journal of Ayurveda Campus”

In this review, researchers reported that Psoralea corylifolia, extensively used in Ayurveda and Traditional Chinese Medicine, exhibits various pharmacological activities, including antioxidant and antidiabetic effects, and is primarily used for treating skin diseases. The authors suggest further clinical trials to explore its therapeutic potential.

Transfollicular Enhancement of Gel Containing Cationic Niosomes Loaded with Unsaturated Fatty Acids in Rice Bran Semi-Purified Fraction

research Transfollicular enhancement of gel containing cationic niosomes loaded with unsaturated fatty acids in rice (Oryza sativa) bran semi-purified fraction

21 citations , April 2012 in “European Journal of Pharmaceutics and Biopharmaceutics”

This study suggests that gel containing OSF3 loaded in niosomes offers high transfollicular penetration for topical anti-androgenic alopecia treatment with minimal systemic effect.

Nicotinic Acid Suppresses Sebaceous Lipid Synthesis of Human Sebocytes via Activating Hydroxycarboxylic Acid Receptor 2 (HCA2)

research 1317 Nicotinic acid suppresses sebaceous lipid synthesis of human sebocytes via activating hydroxycarboxylic acid receptor 2 (HCA2)

April 2018 in “Journal of Investigative Dermatology”

The researchers reported that nicotinic acid normalized excessive sebaceous lipogenesis without affecting basal lipogenesis and suggested potential anti-acne benefits.

Ziziphus Spina-Christi (Christ’s Thorn Jujube): A Drought-Resistant Tree with Medicinal and Industrial Uses

research Ziziphus spina-christi (Christ’s Thorn Jujube)

January 2017 in “Elsevier eBooks”

This review discusses the potential of Ziziphus species and its extracted oil as new therapeutic agents in drug development and highlights the need for further studies to fully exploit this species for human health benefits.

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Community Join

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community Has anyone here tried taking GLA supplements?

1 upvotes 1 year ago

GLA may help with hair loss due to its anti-inflammatory properties and 5ar enzyme inhibition. It's considered potentially more important than biotin, especially for those already using finasteride and dutasteride.

community A person advised me to use pumpkin seed oil instead of minoxidil?

in Minoxidil 9 months ago

Pumpkin seed oil is not a substitute for minoxidil; it acts more like finasteride as a DHT blocker. Minoxidil is necessary for hair growth, and combining it with treatments like PRP or saw palmetto may be beneficial.

community Is it worth using anti-hair loss shampoo?

in Product 2 upvotes 7 months ago

Anti-hair loss shampoos, like the one with rosemary, quillaja, and jaborandi extracts, mainly support scalp health but are not effective for hair regrowth compared to treatments like finasteride or minoxidil. Ketoconazole 2% is noted as the only effective anti-hair loss shampoo, while others are often considered scams.

community Anti inflammatories as an adjunct treatment

1 upvotes 8 months ago

Anti-inflammatories like curcumin, quercetin, and vitamin E may help with hair loss when used alongside treatments like finasteride and dutasteride. Ketoconazole is also noted for reducing scalp inflammation and improving scalp health.

community Anti-androgen use causing testicular pain?

in Finasteride/Dutasteride 5 upvotes 1 year ago

Switching from topical finasteride to oral Dutasteride and using Fluridil caused persistent testicular discomfort. The discomfort did not subside after stopping Fluridil, raising concerns about Dutasteride's role.

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Learn

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learn GT20029

What is GT20029 and how does it work as a topical anti-androgen for hair loss? GT20029 is a topical anti-androgen that degrades androgen receptors to combat hair loss.

learn Aminexil

Aminexil: Can I combine it with anti-hair loss shampoos or will it lose effectiveness? You can safely combine Aminexil with anti-hair loss shampoos for enhanced effectiveness.

learn Cetirizine

What makes cetirizine a unique anti-inflammatory option for your scalp? Laboratory work reports that cetirizine lowers PGD2 and other inflammatory mediators, which is why researchers have proposed it for the scalp. There is no approved topical product and the clinical evidence is one small unblinded pilot study in pattern hair loss, so scalp use is off-label and experimental.

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Clinics

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All 77 clinic results →

Experts

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16
Dermatologist
Andi Iryanti, M. Biomed
Indonesia

Andi Iryanti, M. Biomed