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Glossary Alopecia Areata

autoimmune disorder causing patchy hair loss on scalp and body

Alopecia Areata (AA) is an autoimmune condition where the body's immune system mistakenly attacks hair follicles, leading to patchy hair loss on the scalp and other areas of the body. This condition can affect individuals of all ages and often results in round, smooth bald patches, though the extent and pattern of hair loss can vary widely.

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Research

5 / 1000+ results

research PUVA treatment of alopecia areata partialis, totalis and universalis: audit of 10 years' experience at St John's Institute of Dermatology

105 citations , December 1995 in “British journal of dermatology/British journal of dermatology, Supplement”

This retrospective study concluded that PUVA treatment is generally ineffective for alopecia areata, with low effective success rates for partialis, totalis, and universalis types.

research Possible involvement of partial biotinidase deficiency in alopecia areata

6 citations , September 1996 in “Journal of the European Academy of Dermatology and Venereology”

This study found that biotin supplementation improved biotinidase activity and led to clinical remission in some patients with alopecia areata.

research Possible involvement of partial biotinidase deficiency in alopecia areata

1 citations , September 1996 in “Journal of the European Academy of Dermatology and Venereology”

In this study, biotin supplementation improved biotinidase activity and led to clinical remission in some patients with alopecia areata.

research 84 Partial restoration of scalp microbiota in alopecia areata with JAK inhibitors

November 2023 in “Journal of Investigative Dermatology”

In this study, patients with alopecia areata displayed altered scalp microbiota compared to healthy controls, and treatment with JAK kinase inhibitors largely restored these microbial changes, providing insights into the potential role of the skin microbiome in alopecia areata.

research Partial Response of Severe Alopecia areata to Cyclosporine A

30 citations , January 1999 in “Dermatology”

This study found that cyclosporine A may lead to partial hair regrowth in 50% of patients with severe alopecia areata who do not respond to standard treatments.

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Community Join

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community Prolactin the Cause of Hair Loss? ABS-201 the Cure?

29 upvotes 2 months ago

Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.

community Low dose corticosteroids for treatment of DUPA?

3 upvotes 3 years ago

community Is it ok to take Xeljanz (A jak inhibitor) while taking finasteride?

2 upvotes 9 years ago

The conversation is about whether it is safe to take Xeljanz, a JAK inhibitor, while also taking finasteride for hair loss. The concern is that Xeljanz weakens the immune system, which could be risky.

community What is this pigmentation around my follicles?

in Chat 29 upvotes 1 year ago

The conversation discusses potential causes of pigmentation around hair follicles, suggesting sebum buildup, autoimmune conditions, or dermatitis. Treatments mentioned include finasteride, dutasteride, and an anti-inflammatory diet, with a recommendation to consult a doctor for a proper diagnosis.

community Calling out diffuse thinners here -- Have you ruled out other factors?

in Treatment 54 upvotes 1 year ago

Diffuse hair loss is often linked to genetics but can also be due to health issues like thyroid problems and low vitamin or iron levels. Treatments include finasteride, minoxidil, and dutasteride, with some seeing improvements after addressing health issues.

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Learn

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learn Overview

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn GHK-Cu

Heard alopecia areata leaves scar-like spots? Some peptides are helping those areas regrow hair. Alopecia areata patches usually still have living follicles. Peptides are being studied as a possible add-on, but the evidence is small and early. See a dermatologist for treatment.

learn Salicylic acid

What makes alopecia areata different from other types of hair loss, and can topical Salicylic acid treatments help regrow the affected areas? Alopecia areata is an autoimmune condition, and salicylic acid does not promote hair regrowth.

learn Baicapil

Struggling with patchy hair loss like alopecia areata? Baicapil might help by reducing inflammation and reactivating growth. There is no published trial of Baicapil in alopecia areata. The anti-inflammatory and hair-density claims come from the ingredient's manufacturer and from laboratory work on its plant extracts, in people with androgenetic-type hair loss rather than autoimmune patchy hair loss.

learn Bimatoprost

Is bimatoprost effective for people with alopecia areata? Bimatoprost may stimulate hair growth but lacks strong evidence for alopecia areata.

learn Cetirizine

Could cetirizine help control autoimmune triggers in alopecia areata? No published trial has tested cetirizine in alopecia areata; one registered trial has not reported results. Small trials in pattern hair loss report modest benefit, so any use for alopecia areata is off-label and unproven.

learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

learn Baricitinib

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

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