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Estradiol

Estrogen hormone, prescribed in tablet, patch and gel forms

Estradiol (E2), also called oestrogen, oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of female reproductive cycles such as estrous and menstrual cycles. Estradiol is responsible for the development of female secondary sexual characteristics such as the breasts, widening of the hips and a female pattern of fat distribution. It is also important in the development and maintenance of female reproductive tissues such as the mammary glands, uterus and vagina during puberty, adulthood and pregnancy. It also has important effects in many other tissues including bone, fat, skin, liver, and the brain.

Information, not medical advice. Talk to a licensed doctor or pharmacist before starting or changing a treatment.

Research 10

  1. Modulation of Chemotherapy-Induced Human Hair Follicle Damage by 17-β Estradiol and Prednisolone: Potential Stimulators of Normal Hair Regrowth by “Dystrophic Catagen” Promotion?Journal of Investigative Dermatology · 2008 · 19 citations
  2. Therapeutic Efficacy of a Combination Therapy of Topical 17α-Estradiol and Topical Minoxidil on Female Pattern Hair Loss: A Noncomparative, Retrospective EvaluationAnnals of Dermatology · 2017 · 11 citations
  3. Reversal of the hair loss phenotype by modulating the estradiol-ANGPT2 axis in the mouse model of female pattern hair lossJournal of Dermatological Science · 2018 · 11 citations
  4. Efficacy of Topical Finasteride 0.5% vs 17α-Estradiol 0.05% in the Treatment of Postmenopausal Female Pattern Hair Loss: A Retrospective, Single-Blind Study of 119 PatientsDermatology practical & conceptual · 2020 · 19 citations
  5. 17α‐estradiol induces aromatase activity in intact human anagen hair follicles ex vivoExperimental Dermatology · 2002 · 71 citations
  6. Effect of gender-affirming hormone therapy on hair growth: a systematic review of the literatureClinical and Experimental Dermatology · 2023 · 21 citations
  7. 17β-Estradiol and ICI-182780 regulate the hair follicle cycle in mice through an estrogen receptor-α pathwayAmerican Journal of Physiology-Endocrinology and Metabolism · 2000 · 80 citations
  8. The use of cyproterone acetate/ethinyl estradiol in hyperandrogenic skin symptoms – a reviewThe European Journal of Contraception & Reproductive Health Care · 2017 · 25 citations
  9. Effects of 17-β-Estradiol and ICI 182 780 on Hair Growth in Various Strains of MiceJournal of Investigative Dermatology Symposium Proceedings · 1999 · 34 citations
  10. Clinical and phototrichogrammatic evaluation of estradiol replacement therapy on hair growth in postmenopausal Japanese women with female pattern hair loss: a pilot studyInternational Journal of Women's Dermatology · 2023 · 4 citations
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Posts 20

  1. Androsterone as a Neurosteroid Replacement Strategy for 5α-Reductase Inhibitor–Associated Sexual and Affective DysfunctionReddit · 15 Jul 2026
  2. Finasteride- how serious is the increase in estrogen?Reddit · 2 Jan 2022
  3. 25 years on Finasteride and it's not working anymore.Reddit · 14 Mar 2026
  4. 22M High Estrogen after blood testReddit · 1 Feb 2026
  5. I hear people always say that you don't need DHT as an adult.Reddit · 13 Aug 2026
  6. Estradiol (E2), Testosterone and DHT levels after 1 month on DutasterideReddit · 27 Nov 2024
  7. 19 months Topical Min/Fin - 7 months HRTReddit · 10 Jun 2026
  8. ( not fear mongering) finasteride breast enlargement reducing dose.Reddit · 27 Oct 2025
  9. Those who have taken dutasteride what was your experience?Reddit · 13 Dec 2025
  10. 4 years on Finasteride/1mg daily and male breast cancerReddit · 5 Jan 2025
  11. I’m considering stopping finasterideReddit · 27 Dec 2025
  12. Lowering high estradiol induced by finasteride with anastrazole (Arimidex).Reddit · 16 Sept 2017
  13. Dutasteride only might be the best ROIReddit · 23 Feb 2026
  14. Using an aromatase inhibitor (estrogen blocker) with finasteride to eliminate side effects?Reddit · 18 Jun 2018
  15. Finasteride and TRT simultaneouslyReddit · 12 Apr 2026
  16. Do estrogens do anything for hair loss that finasteride doesn't already do?Reddit · 9 Dec 2023
  17. 3 Months on Finasteride + Oral Minoxidil – Very Happy with Early ResultsReddit · 23 Jun 2026
  18. Well… I Did It. Estrogen Saved My HairlineReddit · 18 Sept 2024
  19. Has anybody tried injectable AHK-Cu for hair?Reddit · 24 Aug 2026
  20. 11 months of 1.5 mg Finasteride with blood samplesReddit · 13 Jun 2024
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