X-Linked Mental Retardation
June 1991
in “
Journal of Medical Genetics
”
TLDR X-linked mental retardation includes various syndromes with both mental and physical abnormalities.
The document discussed the classification of mental retardation (MR) based on IQ ranges and explored various syndromes associated with X-linked mental retardation (XLMR). It categorized MR into mild, moderate, severe, and profound based on standard deviations from the mean IQ. The text listed numerous syndromes linked to XLMR, including Fragile X syndrome, Golabi-Ito-Hall syndrome, and others, often associated with physical and developmental abnormalities such as brachycephaly, macro-orchidism, and cryptorchidism. Additionally, it mentioned conditions like focal dermal hypoplasia and keratosis follicularis-MR syndrome, which were associated with alopecia and other dermatological features.