Development and Validation of New UV-Visible Spectrophotometric Method for the Estimation of Minoxidil in Bulk and Pharmaceutical Dosage Form

May 2025 in “ International Journal of Pharmacognosy and Chemistry ”

Y Kesava, D Jothieswari, Kumar Amarjeet, Kusuma Kusuma, Ankitha Ankitha, Paul Elisha, Richa Halder

minoxidil UV-visible spectrophotometric method Rogaine

TLDR A new accurate and cost-effective method was developed to measure Minoxidil in different forms.

The study developed and validated a simple, precise, and cost-effective UV-visible spectrophotometric method for estimating Minoxidil in bulk and pharmaceutical dosage forms. The method demonstrated high accuracy with recovery results ranging from 99.57% to 100.55% and a correlation coefficient of 0.9993. The limits of detection (LOD) and quantification (LOQ) were 5.08 μg/ml and 15.38 μg/ml, respectively. The method was validated for linearity, accuracy, precision, ruggedness, and robustness, proving to be economical and effective for determining Minoxidil in various formulations.

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