A Randomized, Prospective, Single-Blind Clinical Trial: Comparative Study of the Efficacy and Safety of Different Minoxidil Formulations in Treating Androgenic Alopecia

    March 2026 in “ Journal of medical & health sciences review. ”
    Saleem Khan, Sadia Sabir, Muhammad Aqeel Shah, Fazli Rabi, Zulfiqar Ali
    TLDR Both 5% minoxidil foam and liquid effectively treat hair loss, with foam slightly preferred.
    This study was a 12-month, randomized, prospective, single-blind clinical trial conducted at Buner Medical Complex to compare the efficacy and safety of 5% minoxidil foam and 5% minoxidil liquid solution in treating androgenic alopecia (AGA) in male patients. Both formulations were found to be effective, showing statistically significant improvements in hair diameter (12.4-12.6%) and hair density (2.4-3.1%) over 12 weeks. While both treatments were well-tolerated and effective, the foam formulation showed a slight advantage in patient satisfaction and density gain. The study supports the use of minoxidil as a first-line treatment for AGA, with the choice of formulation depending on patient preferences and treatment goals.
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