Systematic review of the use of platelet-rich plasma in aesthetic dermatology

The 2015 systematic review analyzed the efficacy of platelet-rich plasma (PRP) in aesthetic dermatology, including its use in androgenetic alopecia, scar revision, acne scars, skin rejuvenation, dermal augmentation, and striae distensae. The review included 22 manuscripts, with evidence suggesting PRP's benefits in hair growth and skin rejuvenation. PRP showed positive results in hair loss treatment, with improved hair volume and quality, but was less effective in severe alopecia cases. In scar revision, PRP combined with other treatments like fat grafting or laser therapy showed significant improvements. For acne scars, PRP used with fractional laser therapy led to substantial improvements and reduced recovery times. Skin rejuvenation treatments with PRP improved skin quality metrics. Despite these positive findings, the review emphasized the need for more controlled studies, including split-face comparisons, to confirm PRP's efficacy and establish best practices, as the document lacked specific participant numbers for the referenced studies.