A Case-Control Study of Physical Activity, Obesity, and Energy Intake and the Risk of Kidney Cancer
June 2006
in “
American Journal of Epidemiology
”
TLDR Being obese and eating too many calories may increase the risk of kidney cancer, but physical activity doesn't seem to affect this risk.
The study investigated the relationship between physical activity, obesity, energy intake, and the risk of kidney cancer. It involved 810 cases of histologically confirmed incident kidney cancer and 3,106 controls aged 20-76 years from Canada, with data collected from 1994-1997. The study found that obesity, defined as a body mass index (BMI) of 30 kg/m² or higher, significantly increased the risk of kidney cancer in both men (odds ratio [OR] 2.66, 95% confidence interval [CI] 1.91-3.70) and women (OR 2.45, 95% CI 1.78-3.37). High calorie intake was also associated with an increased risk of kidney cancer for both men (OR 1.48, 95% CI 1.05-2.09) and women (OR 1.42, 95% CI 1.02-1.99). However, recreational physical activity did not show a significant effect on kidney cancer risk. The study suggests a possible synergistic effect between obesity and excess calorie intake on kidney cancer risk.
