Acute Severe Hypokalemia Caused by Treatment of Tongue Squamous Cell Carcinoma with Docetaxel and Cisplatin: A Case Report

A case report highlights a patient with tongue squamous cell carcinoma who developed severe hypokalemia during chemotherapy with docetaxel and cisplatin, with potassium levels dropping to 1.85 mmol/L. The patient experienced significant muscle weakness but recovered after receiving potassium supplements. The report emphasizes that while hypokalemia is a rare side effect of docetaxel, it can be severe, and the mechanism is not well understood. It underscores the importance of vigilant monitoring by healthcare providers for adverse effects, considering individual patient differences, and regularly checking electrolyte levels to prevent life-threatening complications.