Recent developments in luteolin-loaded nanoformulations for enhanced anti-carcinogenic activities: insights from in vitro and in vivo studies

This review highlights the potential of luteolin, a flavonoid with anti-carcinogenic properties, as a safer alternative to traditional chemotherapy, which often causes side effects like hair loss. Despite its benefits, luteolin's therapeutic potential is limited by poor bioavailability and solubility. The review examines how encapsulating luteolin in nanoformulations can enhance its effectiveness, offering a promising strategy for cancer treatment. By comparing the efficacy of luteolin with and without nanoformulations, the review suggests that luteolin-loaded nanoformulations could improve cancer care and outcomes globally.