[Reactions and side effects of ovulation inhibitors on the skin].

The document reviewed dermatological side effects associated with oral contraceptive (o.c.) use, noting that increased pigmentation was linked to estrogen-induced melanin-stimulating hormone production. O.c. use decreased sebum production, benefiting acne and seborrhea oleosa, especially with chlormadinon acetate due to its antiandrogenic effect. Hair growth was affected, with androgenetic alopecia often linked to nortestosterone-containing preparations. Other observed conditions included peroral dermatitis, lupus erythematosus, allergic reactions, and porphyria cutanea tarda, the latter associated with liver dysfunctions. Vaginal candidosis and herpes gestationes were more common among o.c. users. A study of 166 patients showed acne improvement with Ovosiston, and increased vaginal fluor indicated higher trichomoniasis and candida mycosis rates. Liver damage was confirmed in all porphyria cutanea tarda cases.