Quality Control In Compounded Minoxidil Solutions

    December 2024 in “ Brazilian Journal of Development
    Reicieri Marcelo Guareschi, Ricardo Benites Bertasso, Rodrigo Andrade, Esdras Melo de Souza, Bruno Nascimento
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    Studysummary This study evaluated the quality of 5% Minoxidil samples and found that only one out of three magistral formulations met acceptance criteria, highlighting the need for stricter quality control in custom pharmacy preparations to ensure their therapeutic efficacy.
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    The study assessed the quality of 5% Minoxidil solutions for alopecia treatment by analyzing four samples—three compounded in pharmacies and one industrialized—using physical-chemical tests like UV-Vis spectrophotometry. Only one compounded sample met the Brazilian Pharmacopoeia's standards, indicating potential issues with weighing or raw material quality in the others. The study concludes that stricter quality control in compounding pharmacies is essential to ensure the therapeutic efficacy of Minoxidil formulations.
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