Promoting Effects of Herbal Extracts Mixtures on Hair Growth in C57BL/6 Mice

In 2009, a study was conducted to investigate the effects of herbal extract mixtures on hair growth in an alopecia model of C57BL/6 mice. The study involved four experimental groups: distilled water (negative control), 25% ethanol (vehicle control), and two herbal extract mixtures (HE-1 and HE-2). HE-1 included Polygonum and Brassica campestris extracts, and HE-2 included Mulberry root and Gardenia extracts. The test compounds were topically applied to the mice daily for three weeks. The results showed that the topical application of the herbal extracts (HE-1 & 2) for two weeks to dorsal skin accelerated hair re-growth remarkably faster than that of the distilled water group. The study concluded that the herbal extract mixtures used may have hair-growth promoting activities and could be useful for treatment for male pattern baldness or alopecia in humans.