Do Pregnancy And Parenthood Influence The Long-Term Course Of Polycystic Ovary Syndrome (PCOS)? Follow-Up Data From The Prospective LIPCOS Study (Lifestyle Intervention In Polycystic Ovary Syndrome)

    January 2017 in “ mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich) ”
    L Sperl
    TLDR Pregnancy and parenthood do not significantly change PCOS symptoms, but childless women have less hirsutism and weight gain.
    The LIPCOS study analyzed 24 out of 67 participants with Polycystic Ovary Syndrome (PCOS) over a long-term period, comparing mothers and childless women. The study found no significant differences in testosterone, DHEAS, SHBG, and LH/FSH ratio between the two groups. However, childless women experienced less hirsutism (p=0.009) and weight gain. Mothers reported shorter menstrual cycles over time (from 41.0 days at t-10 to 38.4 days at t0) and more regular daily routines (p=0.017).
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