Porokeratotic Eccrine Ostial and Dermal Duct Nevus: A Report of Rare Late-Onset Solitary Lesion
April 2025
in “
Clinical Cosmetic and Investigational Dermatology
”
TLDR A rare skin lesion in a 64-year-old woman was successfully treated with a laser, showing minimal redness and no return after one month.
This case report details a rare late-onset instance of porokeratotic eccrine ostial and dermal duct nevus (PEODDN) in a 64-year-old woman, which is atypical as it usually presents congenitally or in early childhood. The lesion was treated with CO2 laser therapy, resulting in minimal residual erythema and no recurrence after one month. The report highlights the necessity of histopathological examination for accurate diagnosis and discusses a potential genetic basis involving GJB2 mutations. It stresses the importance of a multidisciplinary approach in managing PEODDN and suggests that future research should explore genetic insights and novel treatments.
