Phytochemical analyses of Ziziphus jujuba Mill. var. spinosa seed by ultrahigh performance liquid chromatography-tandem mass spectrometry and gas chromatography-mass spectrometry

    January 2013 in “Analyst”
    Bao Yang, Huiying Yang, Feng Chen, Yuan‐Zhao Hua, Yueming Jiang
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    TLDR The study found that Ziziphus jujuba seeds contain beneficial compounds for treating insomnia and anxiety and that the methods used are effective for assessing their quality.
    In the 2013 study, researchers used ultrahigh performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) and gas chromatography-mass spectrometry (GC-MS) to analyze the phytochemical profile of Ziziphus jujuba Mill. var. spinosa seeds. They identified around 50 chemicals, including flavonoid C-glycosides, triterpene acids, and unsaturated fatty acids, with betulinic acid and oleic acid being the most prominent compounds detected by UPLC-MS/MS and GC-MS, respectively. The study found that while the phytochemical profiles were similar across samples, the levels of specific compounds varied. Principal component analysis (PCA) was used to assess the quality differences among the seed samples. The study concluded that UPLC-MS/MS and GC-MS are effective for evaluating the pharmaceutical quality of Z. jujuba seeds, which contain bioactive compounds beneficial for treating conditions like insomnia and anxiety. The number of seed samples analyzed was not mentioned.
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