Pyoderma Gangrenosum Associated with Rheumatoid Arthritis Mimicking Vasculitis

This article presents a case report of a 75-year-old female with rheumatoid arthritis (RA) who developed pyoderma gangrenosum (PG), a rare skin condition characterized by painful, necrotic ulcers. Initially, her ulcerative skin lesions were thought to be vasculitis due to their appearance. However, a skin biopsy confirmed PG through the presence of neutrophilic infiltration, and further tests ruled out vasculitis. The patient was treated with systemic corticosteroids and immunosuppressive therapy, leading to significant improvement. This case underscores the need to consider PG as a differential diagnosis in RA patients with similar skin lesions.