Persistence of Long COVID Symptoms in COVID-19 Survivors Worldwide and Its Potential Pathogenesis: A Systematic Review and Meta-Analysis

August 2021 in “ Narra J ”

Marhami Fahriani, Muhammad Ilmawan, Jonny Karunia Fajar, Helnida Anggun Maliga, Andri Frediansyah, Sri Masyeni, Hanifah Yusuf, Firzan Nainu, Francesco Rosiello, Salin Sirinam, Synat Keam, Youdiil Ophinni

hair loss

TLDR Many COVID-19 survivors experience long-lasting symptoms, including hair loss and psychological issues.

The systematic review and meta-analysis aimed to determine the prevalence of persistent long COVID symptoms, including hair loss, among COVID-19 survivors worldwide. The study found that the global prevalence of prolonged anxiety was 15.76%, chest pain persisted in 10.36% of patients, prolonged depression was found in 4.32% of survivors, and dizziness was presented in 4.83% after recovery. Hair loss was reported by 24.76% of recovered patients, while weight loss was identified in 8.19% of survivors. Prolonged palpitation was experienced by 19.38% of survivors, and sleep difficulty was found in 17.87% of survivors. The study concluded that persistent psychological symptoms are frequently reported among COVID-19 survivors, but the association between COVID-19 severity and the occurrence of persistent long COVID symptoms was not analyzed due to the lack of data. Further studies with a longer duration and larger population are needed to assess the extent of prolonged symptoms and the quality of life of COVID-19 survivors.

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