Pemilihan Obat Anti-Epilepsi (OAE) untuk Penyandang Epilepsi Wanita Usia Subur

    January 2025 in “ Cermin Dunia Kedokteran ”
    Jenita Surianggo, Budi Riyanto Wreksoatmodjo
    TLDR Choose anti-epileptic drugs carefully for women of childbearing age to avoid risks during pregnancy.
    The document discusses the selection of anti-epileptic drugs (AEDs) for women with epilepsy who are of childbearing age. It highlights the importance of carefully choosing AEDs due to potential effects on pregnancy and fetal development, such as teratogenic effects and impacts on neonatal outcomes and neurodevelopment. In Indonesia, first-line AEDs include carbamazepine, valproic acid, phenobarbital, and phenytoin, while second-line options are lamotrigine, levetiracetam, clobazam, and topiramate. The paper emphasizes the need for careful consideration of these drugs' effects when women with epilepsy plan for pregnancy.
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