Pelvic ultrasound and color Doppler findings in different isosexual precocities

The study evaluated the effectiveness of ultrasound and color Doppler analyses in diagnosing different types of isosexual precocities in 69 girls under 8 years old with early breast development and/or pubic hair growth. It found that girls with a pubertal response to the GnRH test had significantly larger uterine sizes and lower uterine artery impedance compared to those with prepubertal responses or isolated pubarche or thelarche. Endometrial echo was more frequently observed in girls with a pubertal response. The findings suggested that sonographic and color Doppler parameters could enhance the diagnosis of GnRH-dependent precocious puberty and help identify which girls might require treatment.