Patch Testing in Allergic Contact Dermatitis from Minoxidil

July 2010 in “ Dermatitis ”

Monica Corazza, Alessandro Borghi, Michela Ricci, Oriele Sarno, Annarosa Virgili

minoxidil androgenetic alopecia pruritus scaling irritant contact dermatitis allergic contact dermatitis seborrheic dermatitis patch testing propylene glycol butylene glycol polysorbate glycerol Rogaine

TLDR Patch testing helps find allergens in minoxidil treatments, but doesn't ensure alternatives will be tolerated.

Topical minoxidil was a safe and effective treatment for androgenetic alopecia, but some patients experienced pruritus and scaling of the scalp due to irritant or allergic contact dermatitis, or seborrheic dermatitis. Patch testing helped identify allergens, with propylene glycol being the most common. Patients allergic to minoxidil could not use any minoxidil preparations, but those allergic to other components might use alternative formulations with different solvents like butylene glycol, polysorbate, or glycerol. However, patch testing did not guarantee tolerance to these alternatives.

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Research cited in this study

4 / 4 results

research Allergic Contact Dermatitis to Topical Minoxidil Solution: Etiology and Treatment

123 citations , February 2002 in “Journal of The American Academy of Dermatology”

Minoxidil can cause skin allergy; use alternative solvents or treatments if allergic.

research Allergic Contact Dermatitis from Minoxidil

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Minoxidil can cause allergic reactions, but testing helps identify the cause.

research Allergic Contact Dermatitis from Minoxidil

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A small percentage of minoxidil users may develop an allergic skin reaction.

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