Overexpression of Neurotrophin 4 in Skin Enhances Myelinated Sensory Endings but Does Not Influence Sensory Neuron Number

July 2006 in “ The Journal of Comparative Neurology ”

Robin F. Krimm, Brian M. Davis, Teresa Noel, Kathryn M. Albers

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research Differential dependency of unmyelinated and A delta epidermal and upper dermal innervation on neurotrophins, trk receptors, and p75LNGFR.

122 citations , June 1998 in “PubMed”

Neurotrophins regulate nerve growth by balancing promotion and suppression.

research Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation.

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TGF-alpha affects skin thickness, hair growth, and may contribute to psoriasis and papilloma formation.