Optimization of X-ray microplanar beam radiation therapy for deep-seated tumors by a simulation study

    January 2014 in “ Journal of X-Ray Science and Technology ”
    Kunio Shinohara, Takeshi Kondoh, Nobuteru Nariyama, H. Fujita, Masakazu Washio, Yukimasa Aoki
    TLDR Using 100–300 keV X-ray energy is best for treating deep-seated tumors with microplanar beam radiation therapy.
    A Monte Carlo simulation study on microplanar beam radiation therapy (MRT) for deep-seated tumors found that increasing X-ray energy reduced the valley region area at the same beam separation, which is crucial for normal tissue recovery. The study concluded that the optimal X-ray energy range for effective treatment was 100–300 keV, depending on the target tumor's peak dose and tolerable surface dose. The research proposed parameters for further optimization of MRT for deep-seated tumors.
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