Oligosecretory Multiple Myeloma: Unusual Presentation of a Rare Clinical Disease
April 2017
in “
Medicina Clínica (english Edition)
”
TLDR A woman with a rare form of multiple myeloma had a headache and a skull mass, which led to her diagnosis after tests and a biopsy.
The document describes a case of a 38-year-old female patient with oligosecretory multiple myeloma, a rare form of multiple myeloma characterized by minimal production of monoclonal proteins. The patient presented to the emergency room with a headache and a palpable, painful mass on her right parietal skull, which was soft and without skin discoloration or loss of continuity. Skull radiography and cranial imaging revealed multiple lytic lesions and an extra-axial expansion process with bone destruction. Initial tests did not indicate a monoclonal component in blood and urine, but a high ratio of free light chains led to a bone marrow biopsy, which showed 9% clonal plasma cells. The cranial mass was removed, and histologic analysis confirmed plasmacytoma, leading to the diagnosis of oligosecretory multiple myeloma.
