Oil in a Commercial Standard Diet Needs Its Product Specifications

The study investigated the effects of deteriorated oil in commercial standard diets on 3-week-old weanling Wistar rats over a 19-week period. While the rats showed normal growth and no significant health issues like diarrhea or hair loss, those initially fed the commercial diet exhibited high fecal excretion when switched to a defined diet. Notably, two out of 8 rats in the commercial diet group developed liver abnormalities, and all showed signs of liver and kidney issues. Additionally, this group had altered serum levels of triacylglycerol, glucose, cholesterol, and free fatty acids, aligning with previous findings on deteriorated oil consumption. The study concluded that specific product specifications for oil in commercial diets are necessary to ensure reliable animal experimentation.