Mucocutaneous findings in hematolymphoid neoplasms: An observational study

This observational study, conducted on 172 patients with hematolymphoid neoplasms undergoing chemotherapy, found that 15.6% exhibited skin manifestations related to their malignancy, with 4.6% showing direct malignant cell infiltration. Chemotherapy-induced effects were prevalent, with 46.5% experiencing alopecia, particularly linked to cytarabine and methotrexate, and 47.1% having nail changes. Common non-infectious manifestations included cutaneous hyperpigmentation (31.4%) and xerosis (18.6%). The study emphasized the diagnostic challenges and significant impact on quality of life, advocating for early recognition and a multidisciplinary approach to manage these effects. Limitations included difficulties in histopathological confirmation and drug association due to polypharmacy.